In vitro H+ -K+ ATPase inhibitory potential of methanolic extract of Cissus quadrangularis Linn.

Priyanka Yadav; Aditya Ganeshpurkar; Gopal Rai

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In vitro H+ -K+ ATPase inhibitory potential of methanolic extract of Cissus quadrangularis Linn.

机译：四倍体Cissus quadrangularis Linn甲醇提取物的体外H + -K + ATPase抑制潜力。

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Objective:This study was undertaken to study in vitro H+ -K+ ATPase inhibitory potential of methanolic extract of Cissus quadrangularis Linn.Materials and Mathods:Total phenolic and flavonoid contents from extract was quantified and H+ -K+ ATPase inhibition assay was performed in presence of different concentrations of standard (omeprazole) and methanol extract.Results:Extract showed significant (*P < 0.05) proton pump inhibitory activity in the goat gastric mucosal homogenate which was comparable to standard.Conclusions:These findings showed that methanolic extract of C. quadrangularis Linn. is potent inhibitor of proton pump.

机译：目的：本研究旨在研究四叶草甲醇提取物的体外H + -K + ATPase抑制作用。材料和方法：定量提取提取物中总酚和黄酮含量，并在不同存在下进行H + -K + ATPase抑制试验结果：提取物在山羊胃粘膜匀浆中显示出显着的（* P <0.05）质子泵抑制活性，与标准品相当。结论：这些发现表明四角梭菌的甲醇提取物。是质子泵的有效抑制剂。

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《Pharmacognosy Research》 |2012年第2期|共页
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Priyanka Yadav; Aditya Ganeshpurkar; Gopal Rai;
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中图分类药学;
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7. In vitro H+ -K+ ATPase inhibitory potential of methanolic extract of Cissus quadrangularis Linn. [O] . Yadav, Priyanka, Ganeshpurkar, Aditya, Rai, Gopal 2012

机译：四倍体Cissus quadrangularis Linn甲醇提取物的体外H + -K + ATPase抑制潜力。

In vitro H+ -K+ ATPase inhibitory potential of methanolic extract of Cissus quadrangularis Linn.

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