In vitro anti-plasmodial activity of three herbal remedies for malaria in Ghana: Adenia cissampeloides (Planch.) Harms., Termina liaivorensis A. Chev, and Elaeis guineensis Jacq

Kofi Annan; K. Sarpong; C. Asare; R. Dickson; KI. Amponsah; B. Gyan; M. Ofori; SY. Gbedema

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In vitro anti-plasmodial activity of three herbal remedies for malaria in Ghana: Adenia cissampeloides (Planch.) Harms., Termina liaivorensis A. Chev, and Elaeis guineensis Jacq

机译：三种针对加纳疟疾的草药的体外抗疟原虫活性：顺德阿德尼亚（Adenia cissampeloides）（Planch。）危害，Termina liaivorensis A. Chev和Elaeis guineensis Jacq

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Background:Herbal remedies of Adenia cissampeloides, Terminalia ivorensis, and Elaeis guineensis among others have been used in Ghana for the treatment of various ailments including malaria. However, most of these remedies have not been scientifically investigated.Objective:This study, therefore, seeks to investigate the anti-plasmodial activity of these plants.Materials and Methods:The ethanolic extracts of A. cissampeloides stem, T. ivorensis stem bark, and E. guineensis leaves were tested for in vitro anti-plasmodial activity against chloroquine-resistant strains of Plasmodium falciparum. Thin blood films were used to assess the level of parasitemia and growth inhibition of the extracts.Results:The IC 50 of A. cissampeloides, T. ivorensis, and E. guineensis were 8.521, 6.949, and 1.195 μg/ml, respectively, compared to artesunate with IC50 of 0.031 μg/ml.Conclusion:The result of this study appears to confirm the folkloric anti-malarial use these plants.

机译：背景：加纳已经使用了草药，包括加倍虫（Adenia cissampeloides），Terminalia ivorensis和Elaeis guineensis，以治疗包括疟疾在内的各种疾病。然而，大多数这些补救措施尚未进行科学的研究。目的：本研究旨在研究这些植物的抗疟原虫活性。材料与方法：顺子草茎，象牙草茎皮的乙醇提取物，测试了番木瓜和几内亚大肠杆菌叶对恶性疟原虫抗氯喹菌株的体外抗疟原虫活性。结果：与人参相比，A。cissampeloides，T。ivorensis和E. guineensis的IC 50分别为8.521、6.949和1.195μg/ ml。青蒿琥酯的IC50为0.031μg/ ml。结论：本研究结果似乎证实了这些植物的民用抗疟疾作用。

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《Pharmacognosy Research》 |2012年第4期|共5页
作者
Kofi Annan; K. Sarpong; C. Asare; R. Dickson; KI. Amponsah; B. Gyan; M. Ofori; SY. Gbedema;
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机译：来自ElaeisGuineensis jacq的半制备型HPLC纯化5-锡辛烷醇（5-T3）。 BIXA ORELLANA L和对人A375黑色素瘤细胞体外抗癌活性的评估
2. In vitro anti-plasmodial activity of three herbal remedies for malaria in Ghana: Adenia cissampeloides (Planch.) Harms., Termina liaivorensis A. Chev, and Elaeis guineensis Jacq [O] . Kofi Annan, K Sarpong, C Asare, 2012

机译：加纳疟疾三种草药疗法的体外抗疟原虫活性：腺炎Cissploides（Planch。）危害。，TerminaLiacivorensis A. Chev，和Elaeis Guineensis Jacq

In vitro anti-plasmodial activity of three herbal remedies for malaria in Ghana: Adenia cissampeloides (Planch.) Harms., Termina liaivorensis A. Chev, and Elaeis guineensis Jacq

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