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首页> 外文期刊>Physiological Reports >Routine daily physical activity and glucose variations are strongly coupled in adults with T1DM
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Routine daily physical activity and glucose variations are strongly coupled in adults with T1DM

机译：成年人T1DM的日常日常体育活动和血糖变化强烈相关

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AbstractType 1 Diabetes (T1DM) is characterized by altered glucose homeostasis resulting in wide glucose variations throughout a 24-h period. The relationship between routine daily physical activity and glucose variations has not been systematically investigated in adults with T1DM. The objectives of this study were to characterize and quantify the relationship between routine daily activity and glucose variations in a small group of adults with T1DM. Adults with T1DM treated with an insulin pump were recruited for the study. Over a 3-day period, glucose variations were monitored with a continuous glucose monitoring system (CGMS) and routine daily physical activity was assessed using an accelerometer-based physical activity-monitoring band. Simultaneous glucose and physical activity data for one 24-h period were used for analysis. Cross-correlation function and wavelet coherence analyses were employed to quantify the coupling between physical activity and glucose. Twelve subjects were included in the analysis. Cross-correlation function analysis revealed strong coupling between activity and glucose. Wavelet Coherence demonstrated that slower oscillations (120–340 min) of glucose and physical activity exhibited significantly greater coherence (F = 12.6, P  0.0001) than faster oscillations (10 and 120 min). Physical activity and glucose demonstrate strong time and frequency-dependent coupling throughout a 24-h time period in adults with T1DM.
机译：摘要1型糖尿病（T1DM）的特征在于葡萄糖体内稳态改变，从而导致24小时内葡萄糖的广泛变化。成年人的日常糖尿病患者日常日常体育活动与血糖变化之间的关系尚未得到系统的研究。这项研究的目的是表征和量化一小组成年T1DM成年人的日常活动与血糖变化之间的关系。招募了接受胰岛素泵治疗的T1DM成人。在三天的时间内，使用连续葡萄糖监测系统（CGMS）监测葡萄糖变化，并使用基于加速度计的身体活动监测带评估日常的日常身体活动。在一个24小时内同时进行葡萄糖和体育锻炼数据的分析。互相关函数和小波相干分析被用来量化身体活动和葡萄糖之间的耦合。分析中包括十二个受试者。互相关函数分析显示活性和葡萄糖之间的强耦合。小波相干表明，葡萄糖和身体活动的较慢振荡（120-340分钟）与较快振荡（10和120分钟）表现出显着更高的相干性（F = 12.6，P <0.0001）。在成年人中，T1DM的整个24小时内，体育锻炼和葡萄糖表现出强烈的时间和频率依赖性。

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