...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>PLOS Neglected Tropical Diseases >Bacteriophage-Fused Peptides for Serodiagnosis of Human Strongyloidiasis
【24h】

Bacteriophage-Fused Peptides for Serodiagnosis of Human Strongyloidiasis

机译：噬菌体融合肽对人圆线虫病进行血清诊断

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background Strongyloidiasis, a human intestinal infection caused by the nematode Strongyloides stercoralis, is frequently underdiagnosed and although its high prevalence is still a neglected parasitic disease because conventional diagnostic tests based on parasitological examination (presence of Strongyloides larvae in stool) are not sufficiently sensitive due to the low parasitic load and to the irregular larval output. There is an urgent need to improve diagnostic assays, especially for immunocompromised patients with high parasitic load as consequence of self-infection cycle, which can disseminate throughout the body, resulting in a potentially fatal hyperinfection syndrome often accompanied by sepsis or meningitis.
机译：背景技术线虫病是由线虫类固线虫引起的人类肠道感染，经常被漏诊，尽管其高流行率仍被忽略，因为基于寄生虫学检查的常规诊断测试（粪便中存在线虫幼虫）由于以下原因不够敏感：低的寄生负载和不规则的幼虫输出。迫切需要改进诊断方法，尤其是对于自我感染周期导致寄生虫负荷高，免疫功能低下的患者，这种诊断方法可以在全身传播，导致潜在的致命性过度感染综合征，常常伴有败血症或脑膜炎。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号