Reprogramming Neutral Lipid Metabolism in Mouse Dendritic Leucocytes Hosting Live Leishmania amazonensis Amastigotes

Hervé Lecoeur; Emilie Giraud; Marie-Christine Prévost; Geneviève Milon; Thierry Lang

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Reprogramming Neutral Lipid Metabolism in Mouse Dendritic Leucocytes Hosting Live Leishmania amazonensis Amastigotes

机译：重新编程宿主活的利什曼原虫亚马逊变形虫的小鼠树突状白细胞中性脂代谢。

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Background After loading with live Leishmania (L) amazonensis amastigotes, mouse myeloid dendritic leucocytes/DLs are known to undergo reprogramming of their immune functions. In the study reported here, we investigated whether the presence of live L. amazonensis amastigotes in mouse bone marrow-derived DLs is able to trigger re-programming of DL lipid, and particularly neutral lipid metabolism.

机译：背景技术负载活的利什曼原虫（Lish amazonensis）变形虫后，已知小鼠髓样树突状白细胞/ DLs对其免疫功能进行了重新编程。在本文报道的研究中，我们调查了小鼠骨髓衍生的DL中是否存在活的亚马逊线虫amastigotes，是否能够触发DL脂质的重新编程，尤其是中性脂质代谢。

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《PLOS Neglected Tropical Diseases》 |2013年第6期|共14页
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Hervé Lecoeur; Emilie Giraud; Marie-Christine Prévost; Geneviève Milon; Thierry Lang;
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1. Distinct Transcriptional Signatures of Bone Marrow-Derived C57BL/6 and DBA/2 Dendritic Leucocytes Hosting Live Leishmania amazonensis Amastigotes [J] . Emilie Giraud, Hervé Lecoeur, Guillaume Soubigou, PLOS Neglected Tropical Diseases . 2012,第12期

机译：托管活亚马逊利什曼原虫Amastigotes的骨髓衍生C57BL / 6和DBA / 2树突状白细胞的不同转录特征
2. Dendritic cells as host cells for the promastigote and amastigote stages of Leishmania amazonensis: the role of opsonins in parasite uptake and dendritic cell maturation. [J] . Prina E, Abdi SZ, Lebastard M, Journal of Cell Science . 2004,第Pta2期

机译：树突状细胞作为亚马逊利什曼原虫的前鞭毛体和鞭毛体阶段的宿主细胞：调理素在寄生虫摄取和树突状细胞成熟中的作用。
3. Dendritic cells as host cells for the promastigote and amastigote stages of Leishmania amazonensis: the role of opsonins in parasite uptake and dendritic cell maturation [J] . Prina E, Abdi SZ, Lebastard M, Journal of Cell Science . 2004,第2期

机译：树突状细胞作为亚马逊利什曼原虫的前鞭毛体和鞭毛体阶段的宿主细胞：调理素在寄生虫摄取和树突状细胞成熟中的作用
4. Dendritic Cell Activation and Antigen Delivery by Cationic Lipids [C] . Leaf Huang, Weili Yan, Weihsu Chen Controlled Release Society Annual Meeting and Exposition . 2007

机译：树突状细胞的活化和阳离子脂质的抗原传递。
5. Differential regulation of dendritic cell migration after Leishmania major and Leishmania amazonensis infection [D] . Soto Ruiz, Victor Raul 2007

机译：大利什曼原虫和亚马逊利什曼原虫感染后树突状细胞迁移的差异调节
6. Reprogramming Neutral Lipid Metabolism in Mouse Dendritic Leucocytes Hosting Live Leishmania amazonensis Amastigotes [O] . Hervé Lecoeur, Emilie Giraud, Marie-Christine Prévost, 2013

机译：重新编程宿主活的利什曼原虫亚马逊变形虫的小鼠树突状白细胞中性脂代谢。
7. Reprogramming neutral lipid metabolism in mouse dendritic leucocytes hosting live Leishmania amazonensis amastigotes. [O] . Hervé Lecoeur, Emilie Giraud, Marie-Christine Prévost, 2013

机译：在宿主Leishmania amazonensis无鞭毛体的小鼠树突状白细胞中重编程中性脂质代谢。
8. Leishmania mexicana: Purine Metabolism in Promastigotes, Axenic Amastigotes, and Amastigotes Derived from Vero Cells [R] . Hansen, B. D., Webster, H. K., Hendricks, L. D., 1984

机译：Leishmania mexicana：来自Vero细胞的前鞭毛体，无轴鞭毛体和无鞭毛体中的嘌呤代谢

Reprogramming Neutral Lipid Metabolism in Mouse Dendritic Leucocytes Hosting Live Leishmania amazonensis Amastigotes

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