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首页> 外文期刊>PLOS Neglected Tropical Diseases >Fatal Dengue in Patients with Sickle Cell Disease or Sickle Cell Anemia in Cura?ao: Two Case Reports
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Fatal Dengue in Patients with Sickle Cell Disease or Sickle Cell Anemia in Cura?ao: Two Case Reports

机译：库拉索岛镰状细胞病或镰状细胞性贫血患者的致命登革热：两例报道

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摘要

During the past decades dengue has been reported to occur in Cura?ao. Until now fatal cases were never documented. However the 2010–2011 outbreak with 1,822 serologically confirmed cases was associated with four deaths (personal communication). Two of these patients had been previously diagnosed with SCD type HbSC and SCA. SCD is not uncommon in Cura?ao, with a prevalence of approximately 0.25% [1]. Although chronic diseases such as SCD are considered to be a risk factor for development of severe dengue, few cases of children or adolescents have been reported [2].
机译：在过去的几十年中，据报道登革热在库拉索岛发生。到目前为止，从未记录过致命案例。但是，2010年至2011年爆发的血清学确诊病例为1,822例，与4例死亡有关（个人交流）。这些患者中有两个以前被诊断患有SCD HbSC和SCA型。 SCD在库拉索岛并不罕见，患病率约为0.25％[1]。尽管诸如SCD之类的慢性疾病被认为是发展严重登革热的危险因素，但很少有儿童或青少年病例报道[2]。

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