• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>PLOS Neglected Tropical Diseases >Cystic Echinococcosis in the Province of álava, North Spain: The Monetary Burden of a Disease No Longer under Surveillance
【24h】

Cystic Echinococcosis in the Province of álava, North Spain: The Monetary Burden of a Disease No Longer under Surveillance

机译：西班牙北部阿拉瓦省的囊性棘球co虫病：不再受到监视的疾病的货币负担

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Cystic echinococcosis (CE) is endemic in Spain but has been considered non-endemic in the province of álava, Northern Spain, since 1997. However, álava is surrounded by autonomous regions with some of the highest CE prevalence proportions in the nation, casting doubts about the current classification. The purpose of this study is to estimate the frequency of CE in humans and animals and to use this data to determine the societal cost incurred due to CE in the álava population in 2005. We have identified epidemiological and clinical data from surveillance and hospital records, prevalence data in intermediate (sheep and cattle) host species from abattoir records, and economical data from national and regional official institutions. Direct costs (diagnosis, treatment, medical care in humans and condemnation of offal in livestock species) and indirect costs (productivity losses in humans and reduction in growth, fecundity and milk production in livestock) were modelled using the Latin hypercube method under five different scenarios reflecting different assumptions regarding the prevalence of asymptomatic cases and associated productivity losses in humans. A total of 13 human CE cases were reported in 2005. The median total cost (95% credible interval) of CE in humans and animals in álava in 2005 was estimated to range between €61,864 (95%CI%: €47,304–€76,590) and €360,466 (95%CI: €76,424–€752,469), with human-associated losses ranging from 57% to 93% of the total losses, depending on the scenario used. Our data provide evidence that CE is still very well present in álava and incurs important cost to the province every year. We expect this information to prove valuable for public health agencies and policy-makers, as it seems advisable to reinstate appropriate surveillance and monitoring systems and to implement effective control measures that avoid the spread and recrudescence of the disease.
机译：囊性棘球病（CE）在西班牙很流行，但是自1997年以来在西班牙北部的阿拉瓦省一直被认为是非本地病。但是，阿拉瓦被自治区包围，该省是全国CE患病率最高的地区，这令人怀疑关于当前分类。这项研究的目的是估算人畜共患CE的频率，并利用这些数据来确定2005年álava人群中因CE造成的社会成本。我们已经从监测和医院记录中识别出流行病学和临床数据，来自屠宰场记录的中间（绵羊和牛）寄主物种的流行率数据，以及来自国家和地区官方机构的经济数据。在五个不同的情况下，使用拉丁文超立方方法对直接成本（诊断，治疗，人类医疗以及对牲畜内脏的定罪谴责）和间接成本（人类生产力下降以及牲畜生长，繁殖力和产奶量减少）进行了建模反映出有关无症状病例患病率和人类相关生产力损失的不同假设。 2005年总共报告了13例人类CE病例。2005年，阿拉瓦人和动物的CE的总费用中位数（可信区间为95％）估计在61,864欧元之间（95％CI％：47,304-76,590欧元） ）和360,466欧元（95％CI：76,424欧元– 752,469欧元），与人为相关的损失占总损失的57％至93％，具体取决于使用的方案。我们的数据提供了证据，证明CE在阿拉瓦仍然很流行，并且每年给该省带来巨大的成本。我们希望这些信息对公共卫生机构和政策制定者具有重要意义，因为似宜恢复适当的监视和监测系统，并采取有效的控制措施来避免疾病的传播和复发。

著录项

相似文献

  • 外文文献
  • 中文文献
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号