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首页> 外文期刊>PLOS Neglected Tropical Diseases >Comparative Ability of Oropsylla montana and Xenopsylla cheopis Fleas to Transmit Yersinia pestis by Two Different Mechanisms
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Comparative Ability of Oropsylla montana and Xenopsylla cheopis Fleas to Transmit Yersinia pestis by Two Different Mechanisms

机译：蒙太奇和小菜蛾跳蚤通过两种不同机制传播鼠疫耶尔森菌的比较能力

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Background Transmission of Yersinia pestis by flea bite can occur by two mechanisms. After taking a blood meal from a bacteremic mammal, fleas have the potential to transmit the very next time they feed. This early-phase transmission resembles mechanical transmission in some respects, but the mechanism is unknown. Thereafter, transmission occurs after Yersinia pestis forms a biofilm in the proventricular valve in the flea foregut. The biofilm can impede and sometimes completely block the ingestion of blood, resulting in regurgitative transmission of bacteria into the bite site. In this study, we compared the relative efficiency of the two modes of transmission for Xenopsylla cheopis, a flea known to become completely blocked at a high rate, and Oropsylla montana, a flea that has been considered to rarely develop proventricular blockage.
机译：背景通过跳蚤叮咬传播鼠疫耶尔森氏菌可以通过两种机制发生。从细菌性哺乳动物中获取血粉后，跳蚤有可能在下次喂食时传播。这种早期阶段的变速箱在某些方面类似于机械变速箱，但机理尚不清楚。此后，传播在鼠疫耶尔森菌在跳蚤前肠的前庭瓣膜中形成生物膜后发生。生物膜可以阻止甚至有时完全阻止血液的摄入，从而导致细菌反流地传播到咬合部位。在这项研究中，我们比较了两种传播方式的相对效率：Xenopsylla cheopis（一种跳蚤已被高比率完全阻断）和Oropsylla montana（一种被认为很少发展成对肠梗阻的跳蚤）。

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