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首页> 外文期刊>PLOS Neglected Tropical Diseases >No Apparent Reduction in Schistosome Burden or Genetic Diversity Following Four Years of School-Based Mass Drug Administration in Mwea, Central Kenya, a Heavy Transmission Area
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No Apparent Reduction in Schistosome Burden or Genetic Diversity Following Four Years of School-Based Mass Drug Administration in Mwea, Central Kenya, a Heavy Transmission Area

机译:在肯尼亚中部地区姆韦(Mwea),这是一个严重的传播地区,经过四年的校本大规模药物管理后,血吸虫负担或遗传多样性没有明显减少

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Background Schistosomiasis is a debilitating neglected tropical disease that infects over 200 million people worldwide. To combat this disease, in 2012, the World Health Organization announced a goal of reducing and eliminating transmission of schistosomes. Current control focuses primarily on mass drug administration (MDA). Therefore, we monitored transmission of Schistosoma mansoni via fecal egg counts and genetic markers in a typical school based MDA setting to ascertain the actual impacts of MDA on the targeted schistosome population.
机译:背景血吸虫病是一种令人衰弱的被忽视的热带病,全世界感染了2亿多人。为了对抗这种疾病,2012年,世界卫生组织宣布了减少和消除血吸虫病传播的目标。当前的控制主要集中在大规模药物管理(MDA)上。因此,我们在典型的基于学校的MDA设置中通过粪便卵计数和遗传标记监测了曼氏血吸虫的传播,以确定MDA对目标血吸虫病人群的实际影响。

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