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Segmental left ventricular hypokinesis is associated with embolic signals in transcranial Doppler

机译:节段性左心室运动不足与经颅多普勒栓塞信号相关

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INTRODUCTION Global left ventricular (LV) hypokinesis is considered to be the cause of stroke, while the significance of segmental wall motion abnormalities is still unknown.OBJECTIVES The aim of the study was to determine the frequency of embolic signals in the middle cerebral artery in patients with segmental LV wall hypokinesis in the course of coronary artery disease (CAD) with and without stroke.PATIENTS AND METHODS The study included 68 patients (aged 21–87 years) with segmental LV wall hypokinesis (33 patients without and 35 with stroke). The reference group comprised 30 patients (aged 43–76 years) with atherosclerotic risk factors; the control group comprised 37 healthy volunteers (aged 41–71 years). All subjects underwent echocardiography and carotid and transcranial Doppler ultrasound with the detection of microembolic signals.RESULTS Embolic signals were observed significantly more often in patients with segmental LV wall hypokinesis than in the control and reference groups. In patients with CAD and stroke, an increased number of embolic signals (≥3) was observed significantly more often compared with patients without stroke. Compared with other locations, interventricular septum and apex hypokinesis was associated with a higher frequency of embolic signals in the middle cerebral arteries.CONCLUSIONS Segmental LV motion abnormalities in the form of hypokinesis in patients with CAD are associated with the presence of embolic signals in the middle cerebral arteries, which may have clinical significance as a risk factor for stroke.
机译:简介整体左心室运动不足被认为是中风的原因,而节段性壁运动异常的重要性仍未知。目的本研究的目的是确定患者大脑中动脉的栓塞信号频率患者和方法该研究纳入了68例(21-87岁)患有LV室壁功能不全的患者(33例无卒中和35例中风)。参比组包括30例动脉粥样硬化危险因素患者(43-76岁)。对照组包括37名健康志愿者(年龄在41-71岁之间)。所有受试者均接受了超声心动图检查,颈动脉和经颅多普勒超声检查,并检测到了微栓塞信号。结果,在节段性左室壁动力不足的患者中,栓塞信号的发生率明显高于对照组和参考组。在患有CAD和中风的患者中,与没有中风的患者相比,观察到的栓塞信号数量增加(≥3)的频率更高。与其他部位相比,室间隔和心尖运动减退与大脑中动脉栓塞信号的发生频率较高相关。结论CAD患者低速运动形式的节段性左室运动异常与中间栓塞信号的存在有关脑动脉,这可能是中风的危险因素。

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