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Shaping life

机译：塑造生活

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We take our shape for granted. As we do the contours of our eyes and the curves of our heart. But for everything to be sculpted the way Nature has found it best for us to be, cells need to know when to multiply and when to stop multiplying, in addition to knowing how to remain close to one another while dealing with external forces such as the gravitational pull. It all comes down to a very delicate balance between biology and physics. Even a single cell needs to be able to counter surrounding tensions without which it would simply collapse and hence lose its three-dimensional status. Within every cell many different proteins are busy making sure that the cell's tension is sufficient for it not to collapse, whilst others promote cell proliferation and cell binding as an organ is gradually formed. Yes-associated protein - YAP - is one such protein that not only has a role in cell proliferation and tissue regeneration but also in organ shape and alignment.
机译：我们认为我们的形状是理所当然的。当我们做我们的眼睛的轮廓和我们的心脏的弯曲。但是，要以自然界认为最适合我们的方式雕刻所有事物，细胞需要知道何时增殖以及何时停止增殖，除了知道如何在处理外力（例如外力）时保持彼此接近之外引力。这一切都归结为生物学与物理学之间非常微妙的平衡。即使是一个单元，也需要能够抵抗周围的张力，否则，它会简单地塌陷并因此失去其三维状态。在每个细胞中，许多不同的蛋白质忙于确保细胞的张力足以使其不崩溃，而其他蛋白质则随着器官的逐渐形成而促进细胞增殖和细胞结合。是的相关蛋白-YAP-是一种不仅在细胞增殖和组织再生中起作用，而且在器官形状和排列中起作用的蛋白。

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