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The contours of heredity

机译：遗传轮廓

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摘要

Life has its shapes, and depends on all kinds of architecture. It needs a skeleton on which to hang. Blood vessels in which to flow. A brain to house its thoughts. A heart to give it a beat. On a far smaller scale, it needs cells to accommodate all the various components without which there would be no life in the first place. One of the most important being: DNA. DNA itself is found within a defined structure in each of our cells: the nucleus. Within this protective core, our genetic heritage adopts yet other variable conformations depending on a cell's stage in mitosis. One of these conformations is the well-known chromosome. Chromosomes are simply highly-packed DNA, which is an ideal conformation to be in when a cell is about to divide for instance, and chromosomes need to move around. Many different proteins work in unison to keep chromosomes arranged in such a way. One in particular has recently proved to be important in maintaining the shape of packed chromosomes, and is called proliferation marker protein Ki-67.
机译：生活有其形状，并取决于各种建筑。它需要一个可以悬挂的骨架。血管在其中流动。容纳思想的大脑。一颗心给它跳动。在较小的规模上，它需要容纳所有各种组件的单元，否则它们将没有生命。最重要的之一是：DNA。 DNA本身存在于我们每个细胞（细胞核）的特定结构中。在这个保护核心内，我们的遗传遗产会根据细胞在有丝分裂阶段的不同，采用其他可变构象。这些构象之一是众所周知的染色体。染色体只是高度堆积的DNA，例如，在细胞即将分裂且染色体需要四处移动时，这是理想的构象。许多不同的蛋白质共同作用以保持染色体以这种方式排列。最近，一种特别重要的物质被证明对保持染色体的形状很重要，被称为增殖标记蛋白Ki-67。

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