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A short story

机译：短篇小说

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When I was a child I remember seeing little girls and boys of my own age whose arms had not grown to their full length. There were not many but enough for me to find it almost normal. What I did not know is that there were other little boys and girls whose legs had not grown either. But we never saw them. As we never knew of all the little babies who died shortly after birth and whose limbs - and other parts of their bodies - were grossly malformed or simply absent. Such deformities were the doings of a drug known as thalidomide, and the children were known as thalidomide children. My mother refused to take thalidomide to treat her morning sickness when she was pregnant with her first child. Many other mothers, however, did not. And it was not long before the link between thalidomide and gross deformities found in newborns was made. How thalidomide created such handicaps remained a mystery for many years. Today, there are a number of hypotheses, one of which involves the protein cereblon which has turned out to be one of thalidomide's direct targets.
机译：当我还是个孩子的时候，我记得我见过我这个年龄的小男孩和男孩，他们的手臂还没有长到全长。没有多少，但足以让我发现它几乎是正常的。我不知道的是，还有其他一些小男孩和女孩的腿也没有长大。但是我们从未见过他们。我们从来都不知道所有出生后不久就死去的小婴儿，其四肢和肢体的其他部位严重畸形或完全没有畸形。这种畸形是被称为沙利度胺的药物的作用，而这些孩子被称为沙利度胺的孩子。我母亲怀有第一个孩子时，拒绝服用沙利度胺来治疗晨吐。然而，许多其他母亲却没有。不久之后，沙利度胺与新生儿严重畸形之间的联系就建立了。沙利度胺如何造成此类障碍的问题多年来一直是个谜。如今，有多种假设，其中一种涉及大脑神经蛋白质，事实证明它是沙利度胺的直接靶标之一。

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