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Association between adiposity indices and cardiometabolic risk factors among adults living in Puerto Rico

机译:波多黎各成年人体内肥胖指数与心脏代谢危险因素之间的关联

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ObjectiveTo compare the general adiposity index (BMI) with abdominal obesity indices (waist circumference (WC), waist-to-hip ratio (WHR) and waist-to-height ratio (WHtR)) in order to examine the best predictor of cardiometabolic risk factors among Hispanics living in Puerto Rico.DesignSecondary analysis of measurements taken from a representative sample of adults. Logistic regression models (prevalence odds ratios (POR)), partial Pearson's correlations (controlling for age and sex) and receiver-operating characteristic (ROC) curves were calculated between indices of obesity (BMI, WC, WHR and WHtR) and blood pressure, HDL cholesterol (HDL-C), LDL cholesterol (LDL-C), total cholesterol (TC):HDL-C, TAG, fasting blood glucose, glycosylated Hb, high-sensitivity C-reactive protein (hs-CRP), fibrinogen, plasminogen activator inhibitor-1 (PAI-1) and an aggregated measure of cardiometabolic risk.SettingHousehold study conducted between 2005 and 2007 in the San Juan Metropolitan Area in Puerto Rico.SubjectsA representative sample of 858 non-institutionalized adults.ResultsAll four obesity indices significantly correlated with the cardiometabolic risk factors. WHtR had the highest POR for high TC:HDL-C, blood pressure, hs-CRP, fibrinogen and PAI-1; WC had the highest POR for low HDL-C and high LDL-C and fasting blood glucose; WHR had the highest POR for overall cardiometabolic risk, TAG and glycosylated Hb. BMI had the lowest POR for most risk factors and smallest ROC curve for overall cardiometabolic risk.ConclusionsThe findings of the study suggest that general adiposity and abdominal adiposity are both associated with cardiometabolic risk in this population, although WC, WHR and WHtR appear to be slightly better predictors than BMI.
机译:目的比较一般肥胖指数(BMI)与腹部肥胖指数(腰围(WC),腰围与臀围比率(WHR)和腰围与身高比率(WHtR)),以评估心血管代谢风险的最佳预测指标居住在波多黎各的西班牙裔人口中的主要因素。设计对有代表性的成年人样本进行测量的二次分析。在肥胖指数(BMI,WC,WHR和WHtR)和血压之间计算了Logistic回归模型(患病几率(POR)),偏皮尔逊偏相关(控制年龄和性别)和接收者操作特征(ROC)曲线,高密度脂蛋白胆固醇(HDL-C),低密度脂蛋白胆固醇(LDL-C),总胆固醇(TC):HDL-C,TAG,空腹血糖,糖基化Hb,高敏感性C反应蛋白(hs-CRP),纤维蛋白原,纤溶酶原激活物抑制剂1(PAI-1)和心脏代谢风险的总体测量方法.2005年至2007年在波多黎各圣胡安大都会区进行的家庭研究,对象是858名非住院成年人的代表性样本。结果所有四个肥胖指数均显着与心脏代谢危险因素相关。 WHtR对高TC:HDL-C,血压,hs-CRP,纤维蛋白原和PAI-1具有最高的POR; WC对于低HDL-C和高LDL-C和空腹血糖具有最高的POR; WHR的总体心脏代谢风险,TAG和糖基化Hb的POR最高。对于大多数危险因素,BMI的POR最低,总体心脏代谢风险的ROC曲线最小。结论研究结果表明,尽管WC,WHR和WHtR略有增加,但一般肥胖和腹部肥胖都与该人群的心脏代谢风险有关。比BMI更好的预测指标。

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