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Acute Respiratory Distress Syndrome: A Clinical Review:

机译：急性呼吸窘迫综合征：临床评价：

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The acute respiratory distress syndrome (ARDS) is a complex disorder of heterogeneous etiologies characterized by a consistent, recognizable pattern of lung injury. Extensive epidemiologic studies and clinical intervention trials have been conducted to address the high mortality of this disorder and have provided significant insight into the complexity of studying new therapies for this condition. The existing clinical investigations in ARDS will be highlighted in this review. The limitations to current definitions, patient selection, and outcome assessment will be considered. While significant attention has been focused on the parenchymal injury that characterizes this disorder and the clinical support of gas exchange function, relatively limited focus has been directed to hemodynamic and pulmonary vascular dysfunction equally prominent in the disease. The limited available clinical information in this area will also be reviewed. The current standards for cardiopulmonary management of the condition will be outlined. Current gaps in our understanding of the clinical condition will be highlighted with the expectation that continued progress will contribute to a decline in disease mortality.
机译：急性呼吸窘迫综合征（ARDS）是一种复杂的异质病因，其特征是一致且可识别的肺损伤模式。为了解决这种疾病的高死亡率，已经进行了广泛的流行病学研究和临床干预试验，并为研究针对这种疾病的新疗法的复杂性提供了重要的见识。本文将重点介绍ARDS中现有的临床研究。将考虑当前定义，患者选择和结果评估的局限性。尽管已经将大量注意力集中在表征这种疾病的实质损伤和气体交换功能的临床支持上，但相对有限的注意力已经集中在疾病中同样突出的血液动力学和肺血管功能障碍。该领域中有限的可用临床信息也将进行审查。将概述该病心肺治疗的现行标准。我们对临床状况了解的当前差距将突出，并期望持续的进步将导致疾病死亡率的下降。

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