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首页> 外文期刊>Universal Journal of Public Health >Sociodemographic and Nutritional Factors Associated with Adherence to Antiretroviral Therapy in PLWHA in Benin
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Sociodemographic and Nutritional Factors Associated with Adherence to Antiretroviral Therapy in PLWHA in Benin

机译：贝宁PLWHA坚持抗逆转录病毒疗法相关的社会人口统计学和营养因素

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Adherence to antiretroviral treatment (ART) is critical for suppression of viral replication, repletion of CD_(4) cells, avoiding viral resistance, improving immune response and slowing HIV infection progression. This study sought to measure adherence to ART and to determine its associated sociodemographic, lifestyle and nutritional factors in HIV-infected adults taking antiretroviral (ARV). Using a cross-sectional study design, medical records of 991 HIV positive patients who started antiretroviral therapy from July, 1~(st) 2011 to June, 30~(th) 2012 were reviewed. Data were collected in 2014 in 46 HIV/AIDS therapy centers across Benin, The independent variables were sociodemographic, lifestyle, nutritional and therapeutic factors. The main dependent variable was the adherence to the ART. Chi-square test was used to determine the association between dependent and independent variables. A p-value < 0.05 was considered statistically significant. Out of 991 PWLHIV, 30.2% showed poor adherence to ARV. Factors associated with ART adherence were social network (p<0.001), gender (p=0.020) and nutritional status based on body mass index (p=0.006). The prevalence of non-adherence to ART was high in PLWHA taking ARV. Efforts are needed to improve adherence to antiretroviral therapy in PLWHA in Benin. Intensive adherence counseling should be provided to all patients before initiation of antiretroviral therapy. Health care providers must contribute to social networking in patients and ensuring nutritional support to them.
机译：坚持抗逆转录病毒治疗（ART）对于抑制病毒复制，补充CD_（4）细胞，避免病毒抵抗，改善免疫反应和减慢HIV感染进程至关重要。这项研究试图衡量抗逆转录病毒疗法的依从性，并确定其在接受抗逆转录病毒疗法（ARV）感染HIV的成年人中的相关社会人口统计学，生活方式和营养因素。使用横断面研究设计，回顾了2011年7月1日至2012年6月30日开始进行抗逆转录病毒治疗的991例HIV阳性患者的病历。 2014年在贝宁的46个HIV / AIDS治疗中心收集了数据。独立变量是社会人口统计学，生活方式，营养和治疗因素。主要因变量是对ART的依从性。卡方检验用于确定因变量和自变量之间的关联。 P值<0.05被认为具有统计学意义。在991名PWLHIV中，有30.2％的人对ARV的依从性较差。与ART依从性相关的因素包括社交网络（p <0.001），性别（p = 0.020）和基于体重指数的营养状况（p = 0.006）。服用抗逆转录病毒药物的PLWHA中不坚持抗逆转录病毒疗法的患病率很高。在贝宁，需要努力提高对抗逆转录病毒疗法的依从性。在开始抗逆转录病毒治疗之前，应向所有患者提供强化依从性咨询。卫生保健提供者必须为患者的社交网络做出贡献，并确保为其提供营养支持。

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