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首页> 外文期刊>Ukrainian Biochemical Journal >Age-related changes phospholipids of sterlet in liver and dorsal muscles
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Age-related changes phospholipids of sterlet in liver and dorsal muscles

机译：与年龄相关的肝和背肌中甾体磷脂的变化

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摘要

Study of phospholipids changes peculiarities in the liver and dorsal muscles of sterlet ( Acipenser ruthenus Linnaeus ) may be important to determine the etiology and pathogenesis of fatty liver. We established that the content of total phospholipids in tissues of the liver and dorsal muscles of three-year-old sterlet was less than for two-year-old fish by 15% and 20% ( P ≤ 0.01), respectively. The amount of phosphatidylcholine ( P ≤ 0.05), phosphatidylethanolamine, phosphatidylserine ( P ≤ 0.01), phosphatidylinositol ( P ≤ 0.01) and cardiolipin in the liver of 3-year-old sterlet was lower than for the 2-year-old fish, while quantitative indices for lysophosphatidylcholine and sphingomyelin were slightly increased. Similarly, in the cells of the dorsal muscles, the amount of phospholipid components (except lysophosphatidylcholine) was decreased with age. A decrease in the amount of phosphatidylethanolamine and phosphatidylserine in the dorsal muscles of 3-year-old sterlet was significant. The major phospholipids respective distribution was stable, except for phosphatidylethanolamine and particularly sphingomyelin.
机译：研究磷脂改变的肝脏和背侧肌肉的特殊性可能对确定脂肪肝的病因和发病机制具有重要意义。我们确定，三岁小ster的肝脏和背部肌肉组织中总磷脂的含量分别比两岁小fish鱼少15％和20％（P≤0.01）。 3岁小鱼肝脏中的磷脂酰胆碱（P≤0.05），磷脂酰乙醇胺，磷脂酰丝氨酸（P≤0.01），磷脂酰肌醇（P≤0.01）和心磷脂的含量低于2岁鱼的肝脏。溶血磷脂酰胆碱和鞘磷脂的定量指标略有增加。同样，在背肌细胞中，磷脂成分（溶血磷脂酰胆碱除外）的含量也随着年龄的增长而减少。 3岁小ster背肌中磷脂酰乙醇胺和磷脂酰丝氨酸的含量明显降低。除了磷脂酰乙醇胺，特别是鞘磷脂，主要的磷脂各自的分布是稳定的。

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