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首页> 外文期刊>Ukrainian Biochemical Journal >Effect of glyphosate on the energy exchange in carp organs
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Effect of glyphosate on the energy exchange in carp organs

机译:草甘膦对鲤鱼器官能量交换的影响

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The use of glyphosate as a herbicide in agriculture can lead to the presence of its residues and metabolites (aminomethylphosphonic acid) in food for human consumption and pose a threat to health. The effect of these herbicides on the fish organism at the biochemical level has been insufficiently studied. We studied changes in the content of adenine nucleotides, enzyme activity, quantitative indexes of energy metabolism substrates in carp under the action of glyphosate. It has been found that proteins are the major energy substrate under the influence of glyphosate in the liver, brain, white muscle of carp yearlings. Glyphosphate decreases energy metabolism in the brain of carp and increases it in the white muscles. The growth of activity of catabolic enzymes in the liver under the influence of glyphosate can be attributed to the adaptive remodelling of metabolic pathways for homeostasis and enantiostasis in response to herbicides.
机译:草甘膦在农业中用作除草剂会导致人类食用食品中残留草甘膦和代谢产物(氨基甲基膦酸),并对健康构成威胁。这些除草剂在生化水平上对鱼类生物的影响尚未得到充分研究。我们研究了草甘膦作用下鲤鱼腺嘌呤核苷酸含量,酶活性,能量代谢底物定量指标的变化。已经发现,草甘膦在鲤鱼一岁猪的肝脏,大脑,白肌中,蛋白质是主要的能量底物。草甘膦减少了鲤鱼大脑中的能量代谢,并增加了白肌肉中的能量代谢。草甘膦影响肝脏中分解代谢酶的活性增长,可归因于对除草剂的体内稳态和对映稳态代谢途径的适应性重塑。

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