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首页> 外文期刊>Taiwanese journal of obstetrics and gynecology >The impact of the modified speculum application technique on the?success rates of intrauterine insemination: A randomized controlled study
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The impact of the modified speculum application technique on the?success rates of intrauterine insemination: A randomized controlled study

机译：改良的窥镜应用技术对子宫内授精成功率的影响：一项随机对照研究

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ObjectiveIntrauterine insemination (IUI) is frequently used to treat patients with ovulation disorders, cervical factor, mild male infertility and unexplained infertility. The aim of this study was to investigate the impact of modified speculum application on the success of IUI in patients with unexplained infertility.Materials and methodsThis prospective randomized study reviewed 219 women who had undergone controlled ovarian hyperstimulation (COH)-IUI treatment. In the modified speculum application group (109 patients with 124 cycles), the screw of the vaginal speculum was loosened after passing the internal os with catheter and the vaginal speculum remained in this position to ensure closure of the cervix during the procedure. In the conventional speculum application group (110 patients with 132 cycles), the screw of the vaginal speculum was not loosened to close the lips of cervix after passing the internal os with the catheter and the vaginal speculum was removed after withdrawal of the insemination catheter. The primary outcome was live birth rate.ResultsThe modified and conventional speculum application groups had statistically similar demographic and clinical characteristics. There were no significant differences between the study and the control groups in terms of the clinical pregnancy rate per cycle and per patient (24.1% vs 18.9% and 26.6% vs 22.7%, respectively), as well as the live birth rate per cycle and per patient (19.3% vs 15.1% and 22% vs 18.1% respectively).ConclusionApplying gentle mechanical pressure on the portio vaginalis of the cervix using a vaginal speculum during IUI does not improve pregnancy and live birth rates in patients with unexplained infertility.
机译：目的宫腔内人工授精（IUI）通常用于治疗排卵障碍，宫颈因子，轻度男性不育和无法解释的不育症的患者。这项研究的目的是调查改良的窥镜应用对无法解释的不育症患者IUI成功的影响。材料和方法这项前瞻性随机研究回顾了219位接受过控制性卵巢过度刺激（COH）-IUI治疗的女性。在改良的窥镜应用组（109例，有124个周期）中，阴道窥镜的螺钉在用导管通过内口后松开，阴道窥镜保持在该位置以确保在手术过程中子宫颈闭合。在常规的窥镜应用组（110例患者，具有132个周期）中，在使内窥镜通过导管后，未松开阴道窥镜的螺钉以闭合子宫颈的唇，并且在拔出授精导管后移除了阴道窥镜。主要结果是活产率。结果改良的和常规的窥镜应用组在统计学上具有相似的人口统计学和临床​​特征。在每个周期和每个患者的临床妊娠率（分别为24.1％对18.9％和26.6％对22.7％）以及每个周期的活产率和对照组之间，研究与对照组之间无显着差异。结论：在IUI期间使用阴道窥镜对子宫颈阴道门施加轻微的机械压力并不能改善不明原因不育患者的妊娠和活产率。

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