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Self-Assembly of Double Hydrophilic Poly(2-ethyl-2-oxazoline)- b -poly( N -vinylpyrrolidone) Block Copolymers in Aqueous Solution

机译:双亲水性聚(2-乙基-2-恶唑啉)-b-聚(N-乙烯基吡咯烷酮)嵌段共聚物在水溶液中的自组装

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The self-assembly of a novel combination of hydrophilic blocks in water is presented, namely poly(2-ethyl-2-oxazoline)- b -poly( N -vinylpyrrolidone) (PEtOx- b -PVP). The completely water-soluble double hydrophilic block copolymer (DHBC) is formed via copper-catalyzed polymer conjugation, whereas the molecular weight of the PVP is varied in order to study the effect of block ratio on the self-assembly process. Studies via dynamic light scattering, static light scattering as well as microscopy techniques, e.g., cryo scanning electron microscopy or laser scanning confocal microscopy, show the formation of spherical particles in an aqueous solution with sizes between 300 and 400 nm. Particles of the DHBCs are formed without the influence of external stimuli. Moreover, the efficiency of self-assembly formation relies significantly on the molar ratio of the utilized blocks. The nature of the formed structures relies further on the concentration, and indications of particular and vesicular structures are found.
机译:提出了亲水性嵌段在水中的新颖组合的自组装,即聚(2-乙基-2-恶唑啉)-b-聚(N-乙烯基吡咯烷酮)(PEtOx-b-PVP)。完全水溶性的双亲水性嵌段共聚物(DHBC)是通过铜催化的聚合物共轭形成的,而PVP的分子量却有所变化,以研究嵌段比对自组装过程的影响。通过动态光散射,静态光散射以及显微镜技术(例如,冷冻扫描电子显微镜或激光扫描共聚焦显微镜)的研究表明,在水溶液中形成的球形颗粒的尺寸在300至400nm之间。 DHBC的颗粒形成不受外界刺激的影响。此外,自组装形成的效率极大地取决于所利用的嵌段的摩尔比。形成的结构的性质进一步取决于浓度,并且发现了特定和囊状结构的迹象。

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