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首页> 外文期刊>The British journal of psychiatry : >Optimising antidepressant use in clinical practice: towards criteria for antidepressant selection
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Optimising antidepressant use in clinical practice: towards criteria for antidepressant selection

机译：在临床实践中优化抗抑郁药的使用：选择抗抑郁药的标准

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Background Current treatment for depression in primary care and other out-patient settings demonstrates a pattern that is incongruous with the magnitude of the burden of depression suggested by its associated disability. Aims To review important considerations in current depression treatment with a focus on antidepressant use. Method Factors influencing the undertreatment of depression in real-world settings are examined. Results Patient and clinician behaviour as well as the incentives created by the health care system affect the likelihood of realising effective antidepressant therapy in practice. Conclusions Given the complexities of clinical practice, selection criteria for an antidepressant should include safety, efficacy and tolerability, as well as the ability of the antidepressant to deliver real-world efficacy while balancing health care costs in the long term.
机译：背景技术当前在初级保健和其他门诊患者中对抑郁症的治疗表现出一种与抑郁症相关的残疾所引起的抑郁症负担程度不相符的模式。目的回顾当前抑郁症治疗中的重要注意事项，重点是抗抑郁药的使用。在现实世界中，研究了影响抑郁症治疗不足的方法因素。结果患者和临床医生的行为以及卫生保健系统所产生的激励机制都会影响在实践中实现有效抗抑郁治疗的可能性。结论鉴于临床实践的复杂性，抗抑郁药的选择标准应包括安全性，功效和耐受性，以及抗抑郁药在长期平衡保健成本的同时提供实际疗效的能力。

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