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Predictors of efficacy in depression prevention programmes

机译:抑郁症预防计划的疗效预测指标

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Background Worldwide, 340 million people are affected by depression, with high comorbid, social and economic costs. Aims To identify potential predictors of effect in prevention programmes. Method A meta-analysis was made of 69 programmes to reduce depression or depressive symptoms. Results The weighted mean effect size of 0.22 was effective for different age groups and different levels of risk, and in reducing risk factors and depressive or psychiatric symptoms.Programmes with larger effect sizes were multi-component, included competence techniques, had more than eight sessions, had sessions 60a€“90 60a€“90 min long, had a high quality of research design and were delivered by a health care provider in targeted programmes. Older people benefited from social support, whereas behavioural methods were detrimental. Conclusions An 11% improvement in depressive symptoms can be achieved through prevention programmes. Single trial evaluations should ensure high quality of the research design and detailed reporting of results and potential predictors.
机译:背景技术在全球范围内,有3.4亿人受到抑郁症的影响,并存的社会,经济成本很高。目的确定预防计划中潜在的影响因素。方法对69个程序进行荟萃分析,以减轻抑郁或抑郁症状。结果加权平均效应大小为0.22,适用于不同年龄组和不同风险水平,并能减少危险因素和抑郁或精神症状。具有更大效应大小的程序是多要素的,包括胜任力技术,参加了八次以上的会议,每次会议的时间为60至90分钟60至90分钟,具有高质量的研究设计,并由医疗服务提供者按照有针对性的计划进行。老年人从社会支持中受益,而行为方式却是有害的。结论通过预防计划可以使抑郁症状改善11%。单一试验评估应确保研究设计的高质量以及结果和潜在预测因素的详细报告。

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