Predictors of schizophrenia

ERIKA LAURONEN; GRAHAM K. MURRAY; HANNU KOPONEN; IRENE ISOHANNI; JOUKO MIETTUNEN; JUHA VEIJOLA; KARL-ERIK WAHLBERG; KRISTIINA MOILANEN; LIISA KEMPPAINEN; MATTI ISOHANNI; PEKKA TIENARI; PIRJO M?KI; SAMI R?S?NEN

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Predictors of schizophrenia

机译：精神分裂症的预测因子

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Background Subtle motor, emotional, cognitive and behavioural abnormalities are often present in apparently healthy individuals who later develop schizophrenia, suggesting that some aspects of causation are established before overt psychosis. Aims To outline the development of schizophrenia. Method We drew on evidence from The Northern Finland 1966 Birth Cohort supplemented by selected findings from other relevant literature. Results The main known risk factors in development of schizophrenia are genetic causes, pregnancy and delivery complications, slow neuromotor development, and deviant cognitive and academic performance. However, their effect size and predictive power are small. Conclusions No powerful risk factor, premorbid sign or risk indicator has been identified that is useful for the prediction of schizophrenia in the general population.

机译：背景技术在明显健康的人中经常出现细微的运动，情绪，认知和行为异常，这些人后来会发展为精神分裂症，这表明因果关系的某些方面是在明显的精神病之前就已经建立的。目的概述精神分裂症的发展。方法我们借鉴了1966年芬兰北部队列研究的证据，并补充了其他相关文献中的精选发现。结果精神分裂症发展的主要已知风险因素是遗传原因，妊娠和分娩并发症，神经运动发育缓慢以及认知和学习成绩异常。但是，它们的效果大小和预测能力很小。结论未发现有力的危险因素，病前体征或危险指标可用于预测普通人群的精神分裂症。

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《The British journal of psychiatry :》 |2005年第48期|共页
作者
ERIKA LAURONEN; GRAHAM K. MURRAY; HANNU KOPONEN; IRENE ISOHANNI; JOUKO MIETTUNEN; JUHA VEIJOLA; KARL-ERIK WAHLBERG; KRISTIINA MOILANEN; LIISA KEMPPAINEN; MATTI ISOHANNI; PEKKA TIENARI; PIRJO M?KI; SAMI R?S?NEN;
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中图分类精神病学;
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机译：精神分裂症和老化的正面光线：精神分裂症症状缓解课程和预测因子的评论：Lange等人的荷兰精神病学区中的5年后续研究。
2. Lack of improvement at week 2 predicts later antipsychotic non-response in people with acute exacerbations of schizophrenia or schizophrenia-like psychosis. [J] . Taro Kishi Evidence-based mental health . 2016,第2期

机译：第2周缺乏改善，预示着精神分裂症或精神分裂症样精神病急性加重患者的抗精神病药反应迟钝。
3. Predictors for symptom re-exacerbation after targeted stepwise drug discontinuation in first-episode schizophrenia Results of the first-episode study within the German research network on schizophrenia [J] . Schizophrenia research . 2016,第1期

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4. On Predicting Relapse in Schizophrenia using Mobile Sensing in a Randomized Control Trial [C] . Rui Wang, Weichen Wang, Mikio Obuchi, IEEE International Conference on Pervasive Computing and Communications . 2020

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5. Refining the prediction of risk for schizophrenia: Combining putative genetic and neurodevelopmental measures to predict schizophrenia-spectrum pathology. [D] . Aghevli, Minu Arianne. 2004

机译：完善对精神分裂症风险的预测：结合推定的遗传和神经发育措施来预测精神分裂症的频谱病理。
6. Predictors of Remission Schizophrenia and Bipolar Disorder in Adolescents with Brief Psychotic Disorder or Psychotic Disorder Not Otherwise Specified Considered At Very High Risk for Schizophrenia [O] . Christoph U. Correll, Christopher W. Smith, Andrea M. Auther, -1

机译：患有短暂性精神病或精神病的青少年的缓解精神分裂症和双相情感障碍的预测因子除非另有说明否则认为精神分裂症的风险很高
7. Positive light on schizophrenia and aging: Commentary on course and predictors of symptomatic remission in schizophrenia: A 5-year follow-up study in a Dutch psychiatric catchment area, by Lange et al. [O] . Tanya T. Nguyen, Dilip V. Jeste 2019

机译：精神分裂症和老化的正面光线：精神分裂症症状缓解课程和预测因子评论：Lange等人的荷兰精神病学区中的5年后续研究。

Predictors of schizophrenia

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