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Features of childhood sexual abuse and the development of psychiatric and substance use disorders

机译:儿童期性虐待的特征以及精神和药物滥用障碍的发展

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Background Childhood sexual abuse (CSA) is associated with an increased risk of subsequent psychiatric disorders. Aims To explore the risk associated with features of CSA and examine whether specific associations exist between particular profiles of CSA and the development of specific syndromes. Method In a population-based sample of adult female twins, we used logistic regression to explore the association between features of CSA (reported by the twin and her co-twin) and lifetime major depression, generalised anxiety disorder, bulimia nervosa, panic disorder and alcohol and drug dependence. Results In univariate and stepwise multiple regressions, patterns of predictors differed, although not significantly, across diagnoses. Greater risk was associated with attempted or completed intercourse, the use of force or threats, abuse by a relative, and a negative response by someone who was told about the abuse. Similar patterns were observed with co-twin reports. Conclusions Specific features of CSA differentially increase risk of later psychopathology; however, there do not appear to be unique predictive relationships between features of CSA and the emergence of specific psychiatric disorders.
机译:背景儿童性虐待(CSA)与随后发生精神病的风险增加有关。目的探讨与CSA的特征相关的风险,并检查CSA的特定特征与特定综合征的发展之间是否存在特定的关联。方法在以成年女性双胞胎为基础的人群样本中,我们使用逻辑回归分析探讨了CSA(由双胞胎和她的双胞胎报告)特征与终生重度抑郁症,广泛性焦虑症,神经性贪食症,恐慌症和酒精和药物依赖性。结果在单变量和逐步多元回归中,各诊断之间预测变量的模式虽然不显着,但差异很大。更大的风险与未遂或彻底的性交,使用武力或威胁,亲戚的虐待以及被告知虐待的人的负面反应有关。在双胞胎报告中观察到了类似的模式。结论CSA的特定特征差异性地增加了后期精神病理学的风险;然而,CSA的特征与特定精神病的出现之间似乎没有独特的预测关系。

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