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首页> 外文期刊>The British journal of psychiatry : >Long-term course of cognitive impairment in schizophrenia
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Long-term course of cognitive impairment in schizophrenia

机译：精神分裂症的认知障碍的长期过程

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The aim of this study was to examine the long-term course of cognitive impairment in people with schizophrenia. Forty-three people with schizophrenia were followed up over an average of 33 years along with a control group of 12 matched individuals free from psychosis. Cognitive function was assessed at baseline and follow-up. The participants with schizophrenia were found to show impairment in verbal and non-verbal intelligence at baseline compared with estimated premorbid scores, this was not found in the control group. At follow-up there was a significant decline in non-verbal intelligence over time in participants with schizophrenia compared with controls ( P =0.007). This differential change over time was not seen in verbal intelligence ( P = 0.318).
机译：这项研究的目的是检查精神分裂症患者的认知障碍的长期过程。对平均有33年的精神分裂症患者以及对照组的12名无精神病患者进行了平均33年的随访。在基线和随访时评估认知功能。发现精神分裂症患者在基线时的言语和非言语智力均低于估计的病前评分，而对照组则没有。在随访中，精神分裂症患者的非语言智力随时间的推移与对照组相比显着下降（P = 0.007）。在语言智能中未发现这种随时间的差异性变化（P = 0.318）。

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