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Outcomes of an effectiveness trial of cognitive-behavioural intervention by mental health nurses in schizophrenia

机译:精神分裂症精神卫生护士进行认知行为干预有效性试验的结果

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Background Little is known about the medium-term durability of cognitive-behavioural therapy (CBT) in a community sample of people with schizophrenia. Aims To investigate whether brief CBT produces clinically important outcomes in relation to recovery, symptom burden and readmission to hospital in people with schizophrenia at 1-year follow-up. Method Participants (336 of 422 randomised at baseline) were followed up at a mean of 388 days (s.d.=53) by raters masked to treatment allocation (CBT or usual care). Results At 1-year follow-up, participants who received CBT had significantly more insight ( P =0.021) and significantly fewer negative symptoms ( P =0.002). Brief therapy protected against depression with improving insight and against relapse; significantly reduced time spent in hospital for those who did relapse and delayed time to admission. It did not improve psychotic symptoms or occupational recovery, nor have a lasting effect on overall symptoms or depression at follow-up. Conclusions Mental health nurses should be trained in brief CBT for schizophrenia to supplement case management, family interventions and expert therapy for treatment resistance.
机译:背景在精神分裂症患者的社区样本中,认知行为疗法(CBT)的中期持久性知之甚少。目的探讨在1年的随访中,短暂的CBT是否会在精神分裂症患者的康复,症状负担和住院率方面产生重要的临床结果。方法参加者(根据CBT或常规护理)在平均388天(标准差= 53)中随访,平均388天(标准差= 53)。结果在1年的随访中,接受CBT的参与者的洞察力明显更高(P = 0.021),阴性症状也明显更少(P = 0.002)。简短的疗法可以防止抑郁症,提高见识,防止复发;对于那些确实复发并且延迟入院时间的人,大大减少了住院时间。它没有改善精神病症状或职业恢复,也没有对后续的总体症状或抑郁症产生持久影响。结论应该对心理保健护士进行简短的CBT精神分裂症培训,以补充病例管理,家庭干预和抗药性专家治疗。

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