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首页> 外文期刊>The British journal of psychiatry : >Antipsychotic long-acting injections: prescribing practice in the UK
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Antipsychotic long-acting injections: prescribing practice in the UK

机译：抗精神病药长效注射：在英国开处方

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Background Data from the USA, Australia and Europe suggest that the proportion of patients with schizophrenia prescribed an antipsychotic long-acting injection (LAI) varies from around a quarter to a third. Use of LAIs has been associated with male gender and younger age. Aims To characterise the use of LAIs in people with schizophrenia in three clinical settings in the UK. Method The study used audit data from quality improvement programmes conducted by the Prescribing Observatory for Mental Health. Results Long-acting injections were found to be prescribed for between a quarter and a third of patients, depending on the clinical setting. Flupentixol, risperidone and zuclopenthixol were most commonly prescribed and were combined with an oral antipsychotic in half of cases, frequently constituting high-dose prescribing. The use of LAIs was not consistently associated with age, gender or ethnicity. Conclusions Antipsychotic LAIs are commonly prescribed. We did not replicate previous findings with respect to demographic variables associated with their use.
机译：来自美国，澳大利亚和欧洲的背景数据表明，开具抗精神病长效注射剂（LAI）的精神分裂症患者比例从四分之一到三分之一不等。 LAIs的使用与男性和年轻年龄有关。目的在英国的三种临床环境中表征精神分裂症患者使用LAI的特征。方法该研究使用了由精神卫生处方观察所实施的质量改进计划的审核数据。结果发现，根据临床情况，四分之一至三分之一的患者应开具长效注射剂。氟哌噻吨，利培酮和zuclopenthixol是最常用的处方，在一半的病例中与口服抗精神病药合用，经常构成大剂量处方。 LAI的使用与年龄，性别或种族并不一致。结论通常使用抗精神病药物LAI。我们没有重复关于使用它们的人口统计学变量的先前发现。

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