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首页> 外文期刊>The EPMA journal. >Characteristics of inflammation common to both diabetes and periodontitis: are predictive diagnosis and targeted preventive measures possible?
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Characteristics of inflammation common to both diabetes and periodontitis: are predictive diagnosis and targeted preventive measures possible?

机译：糖尿病和牙周炎常见的炎症特征：可以进行预测性诊断和有针对性的预防措施吗？

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Abstract Diabetes and periodontitis are chronic inflammatory disorders that contribute to each others’ severity and worsen each others’ prognosis. Studies have shown that patients with diabetes are at increased risk of developing periodontitis, and that diabetics with untreated periodontitis have more difficulty controlling serum glucose. Periodontal treatment that reduces gingival inflammation aids in the control of hyperglycemia. Periodontitis is accompanied by gingival bleeding and the production of an inflammatory exudate termed gingival crevicular fluid (GCF) that arises from the inflamed gingival tissues surrounding the teeth. GCF contains byproducts of connective tissue degradation, enzymes from host and bacterial cells, cytokines and other inflammatory mediators, and has been studied for screening blood glucose and for biomarkers of both diabetes and periodontitis. This review focuses on the inter-relationship between diabetes and periodontitis and the biomarkers common to both these diseases that may enable earlier detection, targeted preventive measures and individualized therapeutic intervention of these chronic conditions.
机译：摘要糖尿病和牙周炎是一种慢性炎症性疾病，会加剧彼此的严重程度并恶化彼此的预后。研究表明，糖尿病患者患牙周炎的风险增加，而患有未经治疗的牙周炎的糖尿病患者更难以控制血糖。减少牙龈发炎的牙周治疗有助于控制高血糖症。牙周炎伴有牙龈出血和由牙周围发炎的牙龈组织引起的称为牙龈沟液（GCF）的炎性分泌物的产生。 GCF包含结缔组织降解副产物，来自宿主和细菌细胞的酶，细胞因子和其他炎症介质，并且已被研究用于筛选血糖以及糖尿病和牙周炎的生物标志物。这篇综述着重于糖尿病和牙周炎之间的相互关系以及这两种疾病共有的生物标志物，这些标志物可以对这些慢性病进行早期发现，有针对性的预防措施和个性化的治疗干预。

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