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Rational Use of Drugs and Irrational Drug Combinations

机译:合理使用毒品和不合理用药组合

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Irrational use of Medicines is a global phenomenon. Rational use of drugs may be defined as: Patients receive medications appropriate to their clinical needs, in doses that meet their own individual requirements, for an adequate period of time, and the lowest cost to them and their community. Overuse, polypharmacy and incorrect use of drugs are the most common problems of drug use today. Irrational use of drugs may result due to various reasons at various levels including the prescribing errors and over the counter drugs. Irrational use of medicines may lead to serious negative health and economic consequences. Many irrational drug combinations are available in Indian market. Proper implementation of rational use of drugs will improve the quality of life and result in better community healthcare. Introduction The Alma-Ata declaration, during the International Conference on Primary Health Care in 1978, reaffirms that health is a fundamental human right and the attainment of the highest possible level of health is a most important worldwide social goal.1 Medicines are integral parts of the health care system and modern health care is unthinkable without the availability of necessary medicines. They not only save lives and promote health, but prevent epidemics and diseases too. Medications are undoubtedly one of the weapons of mankind to fight disease and illness. Accessibility to medication is a fundamental right of every person.2 Ever since the accessibility of modern medicine increased all over the world, increasing incidents of its misuse in the form of overprescribing, multi-drug prescribing, use of unnecessary expensive drugs, self medication and overuse of antibiotics and injections have started. Thus, medications are starting to be misused.Irrational drug use is a global phenomenon now. Medically inappropriate, ineffective and economically inefficient use of drugs occur all over the world. The scenario in developing countries is the worst. According to the reports of NRHM India, irrational drug use is a widely pervasive, irrational practice of medicine and is a matter of serious concern, especially for a developing country like India. 3, 4 Definition The concept of rational drug use is age old, as evident by the statement made by theAlexandrian physician, Herophilus, in 300 B.C that “Medicines are nothing in themselves, but are the very hands of god if employed with reason & prudence” 5 In simplest words rational use means “patient receiving appropriate drug to clinical needs, in adequate dose for the sufficient duration and at the lowest cost possible.”As per the WHO (1985), the definition of rational use of medicines – “Patients receive medications appropriate to their clinical needs, in doses that meet their own individual requirements, for an adequate period of time, and at the lowest cost to them and their community.” 6,7 In addition to above definition, which is from the angle of medical therapeutic view, rational use of drugs can also be viewed from the consumers` perspectives. What is rational in a medical sense may not be rational for the consumer and vice versa. For the consumer, the rationality of using a drug is based on the (re)interpretation of its value for daily life, influenced by cultural perceptions and economic conditions.8 In India, therefore it can be a complex one with multiple cultures, religions, dialects and castes. For example, in North-east India, as Malaria is endemic in nature, people may buy and keep a few antimalarial tablets to be consumed whenever bouts of malarial attack comes, never bothering to complete the whole course of the medicine. Or, as most part of north eastern India is tough hilly terrain, people may prefer to spend money on analgesic tablets, and particularly injections to relieve their misery and to be able to carry on their normal works of earning livelihood, while good food and rest would have been better for their health. Therefore, in understanding the actual meaning of
机译:不合理使用药物是一种全球现象。合理使用药物可以定义为:患者在满足他们自身需求的剂量下,在适当的时间段内以其自身和社区最低的费用接受适合其临床需要的药物。滥用,多药房和药物使用不当是当今最常见的药物使用问题。由于各种原因,包括处方错误和非处方药,可能会导致不合理使用药物。不合理使用药物可能导致严重的负面健康和经济后果。印度市场上有许多不合理的药物组合。合理使用药物将改善生活质量,并改善社区医疗保健。引言1978年在国际初级卫生保健会议上发表的《阿拉木图宣言》重申,健康是一项基本人权,实现最高健康水平是世界上最重要的社会目标。1药物是世界卫生组织不可或缺的组成部分。没有必要的药物,卫生保健系统和现代卫生保健是不可想象的。它们不仅可以挽救生命和促进健康,还可以预防流行病和疾病。药物无疑是人类与疾病作斗争的武器之一。药物可及性是每个人的基本权利。2自从现代药物可及性在全世界范围内增加以来,滥用药物的事件以过量开具,多种药物开处方,使用不必要的昂贵药物,自用药和滥用抗生素和注射已经开始。因此,药物开始被滥用。不合理的药物使用现在是全球性的现象。在世界范围内都存在医学上不适当,无效和经济上无效的药物使用情况。发展中国家的情况最糟糕。根据NRHM印度的报告,不合理用药是一种普遍存在的不合理用药实践,是一个令人严重关切的问题,特别是对于像印度这样的发展中国家而言。 3,4定义合理用药的概念已经很久了,亚历山大公元前赫罗菲勒斯医生在公元前300年发表的声明就证明了这一点:“如果药物在理性和审慎的条件下使用,那么药物本身并不重要,而是上帝的掌控者“ 5用最简单的话来说,合理使用是指“患者以适当的剂量以足够的持续时间并以尽可能低的成本获得满足临床需要的适当药物。”根据WHO(1985),合理使用药物的定义是“患者在足够长的时间内,以对他们和社区最低的费用,接受满足其临床需求的药物,以满足他们自己的个人需求。 6,7除了以上定义(从医学治疗的角度看),还可以从消费者的角度看待药物的合理使用。从医学意义上讲,理性对消费者可能不是理性的,反之亦然。对于消费者而言,使用毒品的合理性是基于其对日常生活价值的(重新)解释,受文化观念和经济状况的影响8。因此,在印度,毒品可能是一种具有多种文化,宗教,的方言和种姓。例如,在印度东北部,由于疟疾是地方病,人们可以购买和保存一些抗疟药片,以防疟疾发作,而不必费心去完成整个药疗过程。或者,由于印度东北部的大部分地区处于崎hill的丘陵地带,人们可能更愿意花钱购买止痛药,尤其是打针以减轻痛苦,并能够进行正常的谋生工作,同时享有良好的食物和休息对他们的健康本来会更好。因此,在理解中的实际含义

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