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首页> 外文期刊>The Internet Journal of Neurology >Enteroviral Transverse Myelitis
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Enteroviral Transverse Myelitis

机译：肠病毒横贯性脊髓炎

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We report a case of acute transverse myelitis due to enteroviral infection. Diagnosis was made following positive PCR of cerebrospinal fluid. She was treated with pleconaril, an antienteroviral agent. Enteroviral infection should be considered in the differential diagnosis of acute transverse myelitis. Introduction Transverse myelitis is an acute monophasic inflammatory disorder affecting the spinal cord. Patients may be of any age and present with a subacute paraparesis. CSF examination shows a cellular pleocytosis, often with polymorphs at the outset. Enterovirus infection is an uncommon cause of central nervous system infection, usually occurring in the immunosuppresed. We report a case of an 81-year-old female presenting with enteroviral induced transverse myelitis. We aim to overview the literature on enteroviral myelitis and discuss the possible role for pleconaril in its treatment. Case An 81-year-old woman with a history of breast cancer ten years previously was admitted to hospital in August 2001 with an ascending paraplegia. Three weeks prior to admission she suffered an episode of shingles affecting her right side T8 to T10 dermatomes that resolved spontaneously. Seven days before admission she noticed tingling in the toes and soles of both feet, which subsequently ascended in association with weakness in both legs. Within five days she was unable to walk and subsequently developed painless urinary retention requiring catheterisation. On examination her cognitive function, speech, cranial nerves and optic fundi were normal. She had a flaccid paraparesis and a sensory level at T5. Initial blood tests revealed a low serum sodium (124 mmol/L), an elevated C-reactive protein (66 mg/L) with a normal ESR (12 mm/hr). An urgent MRI scan was performed which revealed high signal within the thoracic and lumbar spinal cord consistent with an acute transverse myelitis (ATM, figure1).
机译：我们报告一例由于肠病毒感染引起的急性横型脊髓炎。脑脊液PCR阳性后进行诊断。她接受了抗肠病毒药物pleconaril的治疗。鉴别诊断急性横型脊髓炎应考虑肠道病毒感染。简介横向脊髓炎是一种急性单相性炎症，影响脊髓。患者可以是任何年龄的亚急性偏瘫患者。脑脊液检查显示细胞多形性增多，一开始常常多态性。肠病毒感染是中枢神经系统感染的罕见原因，通常发生在免疫抑制状态。我们报告了一例81岁女性，表现为肠病毒引起的横突性脊髓炎。我们的目的是概述有关肠病毒性脊髓炎的文献，并讨论pleconaril在其治疗中的可能作用。病例一名十年前有乳腺癌病史的81岁妇女于2001年8月因截瘫而入院。入院前三周，她遭受了带状疱疹的发作，影响了她的右侧T8至T10皮疹，并自发消退。入院前7天，她注意到双脚的脚趾和脚底刺痛，随后由于双腿无力而上升。在五天内，她无法行走，随后出现无痛性尿retention留，需要进行导管插入。经检查，她的认知功能，言语，颅神经和视神经都正常。她在T5时有轻度的轻瘫和感觉水平。最初的血液检查显示血清钠低（124 mmol / L），C反应蛋白升高（66 mg / L），ESR正常（12 mm / hr）。进行了紧急MRI扫描，发现胸椎和腰椎脊髓内有高信号，与急性横贯性脊髓炎相符（ATM，图1）。

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