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首页> 外文期刊>The Internet Journal of Neuromonitoring >Specific Problems in Interpretation of Absolute Values of Spectral Edge Frequency (SEF) in comparison to Bispectral Index (BIS) for Assessing Depth of Anesthesia
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Specific Problems in Interpretation of Absolute Values of Spectral Edge Frequency (SEF) in comparison to Bispectral Index (BIS) for Assessing Depth of Anesthesia

机译：评估麻醉深度的频谱边缘频率（SEF）绝对值与双谱指数（BIS）相比的特定问题

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The spectral edge frequency (SEF) is a milestone in the computer-assisted EEG analysis for assessing the depth of anesthesia. The SEF as well as the bispectral index (BIS) are numerical descriptors of the EEG. For both, SEF and BIS, limits have been reported within which recall and hemodynamic or motor responses to surgical stimuli are unlikely. We studied the SEF at four different states of anesthesia based on individual observations. Further, we compared the SEF and BIS values in relation to the proposed limits at different endtidal concentrations of sevoflurane (1.2 and 2.4 Vol%et) and desflurane (3.0 and 6.0 Vol%et).The SEF and BIS values were assessed according to the proposed limits for SEF (13.65 and 12 Hz) and BIS (60).We found a high interindividual variability and low intrapersonal stability of the SEF values in the awake state. These findings impair the discrimination of awake and sleep state.The mean SEF was outside the target range at both endtidal concentrations of sevoflurane and desflurane. In contrast, mean BIS values at all measuring phases during anesthesia met the goal of < 60.The increased concentrations of anesthetics are not reflected adequately in the phases of excitation and burst suppression activity.Summarizing, a suitable, statistically calculated approximate target limit of SEF as a tool to guide the depth of anesthesia does not seem to be available at the present time. Introduction The idea of target values to guide the depth of anesthesia is intriguing. In this context the development of the spectral edge frequency (SEF) as an univariate descriptor of the EEG was a milestone 1,2 . The SEF is derived from the power spectrum of the computer-assisted EEG.It reflects the frequency below which a defined power of total power spectrum is situated (Figure 1).
机译：频谱边缘频率（SEF）是计算机辅助EEG分析中用于评估麻醉深度的一个里程碑。 SEF以及双谱指数（BIS）是EEG的数字描述符。对于SEF和BIS而言，都已经报道了极限，在此极限范围内，召回和对手术刺激的血液动力学或运动反应不太可能发生。我们基于个人观察研究了四种麻醉状态下的SEF。此外，我们比较了七氟醚（1.2和2.4 Vol％et）和地氟烷（3.0和6.0 Vol％et）在不同潮气浓度下SEF和BIS值与建议限值的关系。提出了SEF（13.65和12 Hz）和BIS（60）的限值。我们发现，处于清醒状态的SEF值存在较高的个体差异性和较低的人际稳定性。这些发现削弱了对清醒和睡眠状态的区分。在七氟醚和地氟醚的潮气浓度下，平均SEF均超出目标范围。相比之下，麻醉期间所有测量阶段的平均BIS值均达到<60的目标。麻醉剂浓度的增加在兴奋和猝发抑制活动的阶段中没有得到充分体现。目前似乎还没有将其作为指导麻醉深度的工具。引言指导麻醉深度的目标值的想法很有趣。在这种情况下，作为EEG的单变量描述符的频谱边缘频率（SEF）的发展是一个里程碑1,2。 SEF是从计算机辅助EEG的功率谱中得出的，它反映了总功率谱的定义功率位于以下的频率（图1）。

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