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首页> 外文期刊>The Internet Journal of Neuromonitoring >Magnetic Resonance Imaging And Computer NLS-Graphy And In Evaluation Of Surgical Intervention Extent For Brain Tumors Treatment.
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Magnetic Resonance Imaging And Computer NLS-Graphy And In Evaluation Of Surgical Intervention Extent For Brain Tumors Treatment.

机译：磁共振成像和计算机NLS图形以及用于脑肿瘤治疗的手术干预范围的评估。

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The article presents generalized estimation of magnetic resonance imaging diagnostic efficiency in comparison with NLS-graphy in evaluation of surgical intervention extent for brain tumors treatment. Introduction Brain tumor eradication extent, especially of malignant one, is the main prognostic issue, affecting lifetime of patients.Detection of primary tumor of brain, its metastases and response degree for following chemo- and radiotherapy is impossible without modern methods of neurovisualization, such as computer NLS-graphy and magnetic resonance imaging (MRI). Diagnostics of early post-operative period (first two days) complications (haematoma, pneumocephalus, ischemic nidus, edema and displacement) and evaluation of carried out surgical intervention extent is also important. However potentials of NLS-research and MRI in evaluation of carried out surgical intervention extent at early post-operative period were not studied before. At the same time attempts to increase lifetime of patients at post-operative period are related to use of new chemotherapeutic and immune preparations, and also various types of radiotherapy. But to use them efficiently, therapists require accurate information about oncotomy extent which today can be acquired only by application of NLS-research and/or MRI at early post-operative period. Taking into account all abovementioned information, the present study, targeted at increasing of NLS-research and MRI application efficiency for patients suffering from brain tumors at early post-operative period, seems to be quite urgent.By application of these modern methods of diagnostics during first two days after surgical intervention into brain, we tried to evaluate extent of carried out resection and thereupon to choose the most rational tactics of patient treatment during post-operative period or to make a decision if there is need in repeated intervention in order to remove remaining tumor masses. Material and methods We examined 101 neurosurgical patients. In 56 cases we carried out NLS-research and MRI both before operation (not later than in 2 weeks) and during first two days after surgical intervention; in the rest 45 cases we carried out only NLS-research during post-operative period. Also we carried out further repeated examinations if the situation required it.NLS-research was fulfilled with “Metatron”-4025 system (the Institute of Practical Psychophysics) with generator frequency of 4.9 GHz and unit of continuous spiral scanning; the system has installed “Metapathia GR Clinical” computer software with three-dimensional visualization of organs feature.MRI was carried out with “Opart” device (Toshiba) with magnetic field intensity of 0.35 T before and after contrast enhancement by paramagnetic in amount of 0.2 ml per 1 kg of patient’s body weight.Age of patients ranged from 31 to 70. They were administered for brain tumor surgical removal. 35 patients suffered from malignant tumors (glioblastoma – in 16 patients, anaplastic astrocytoma – in 10 and metastases – in 9) and 21 – from benign ones (meningioma – in 12, astrocytoma – in 5, oligodendroglioma – in 2, teratoblastoma – in 1 and hemangioblastoma – in 1 patient). 26 tumors were localized in left cerebral hemisphere, 30 – in right cerebral hemisphere. Frontal region of head was affected in 12 patients, temporal region – in 20, parietal region – in 8, occipital region – in 4, parietotemporal region – in 4, occipitoparietal region – in 4 and cerebellar hemispheres – in 4 patients. Results In this study we intentionally did not cover potentials and comparative analysis on NLS-research and MRI in detection of such complication of early post-operative period as haematoma, hygroma and haemorrhage. We concentrated on their potentials to detect presence and identify size of residual tumor depending on post-operative changes of removed tumor bed.According to surgical intervention, total oncotomy was carried out in 32 patients, - subtotal – in 18, partial –
机译：与NLS图像相比，本文介绍了在评估脑肿瘤治疗的外科手术干预程度方面的磁共振成像诊断效率的广义估计。前言根除脑肿瘤的程度，尤其是恶性肿瘤，是影响患者一生的主要预后问题。如果没有现代的神经可视化方法，例如脑部原发肿瘤的检测，其转移以及后续化学疗法和放射疗法的反应程度是不可能的。计算机NLS图像和磁共振成像（MRI）。术后早期（头两天）并发症（血肿，气头，缺血性脑病，水肿和移位）的诊断和评估手术干预的程度也很重要。但是，之前尚未研究过NLS研究和MRI在评估术后早期手术干预程度方面的潜力。同时，尝试增加术后患者的寿命与使用新的化学疗法和免疫制剂以及各种放射疗法有关。但是，为了有效地使用它们，治疗师需要准确的信息，了解有关开菌程度的信息，而如今，只有在术后早期应用NLS研究和/或MRI才能获得这些信息。考虑到上述所有信息，本研究旨在提高术后早期颅脑肿瘤患者的NLS研究和MRI应用效率，这似乎是非常紧迫的。外科手术进入大脑后的前两天，我们试图评估手术切除的程度，然后选择术后最合理的患者治疗策略，或决定是否需要重复干预以去除肿瘤。剩余的肿瘤块。材料和方法我们检查了101名神经外科患者。在56例患者中，我们在手术前（不迟于2周）和手术后的前两天进行了NLS研究和MRI;在其余45例中，我们仅在术后进行NLS研究。如果情况需要，我们还进行了进一步的反复检查。NLS研究是使用“ Metatron” -4025系统（实践心理物理学研究所）完成的，其发生器频率为4.9 GHz，单位为连续螺旋扫描;系统已安装了具有器官三维特征可视化功能的“ Metapathia GR Clinical”计算机软件。在磁场强度为0.35 T的“ Opart”设备（东芝）进行了0.2倍顺磁对比增强之前和之后进行了MRI每1公斤患者体重1毫升。年龄范围从31至70。他们接受了脑肿瘤手术切除。 35例恶性肿瘤（胶质母细胞瘤– 16例，间变性星形细胞瘤– 10例，转移瘤– 9例）和21例良性肿瘤（脑膜瘤– 12例，星形细胞瘤– 5例，少突胶质瘤– 2例，畸胎母细胞瘤– 1例和血管母细胞瘤– 1例）。 26个肿瘤位于左脑半球，其中30个位于右脑半球。头部额叶区域受累12例，颞区– 20例，顶叶区– 8例，枕叶区域– 4例，顶颞区– 4例，枕顶叶区域– 4例，小脑半球– 4例患者。结果在这项研究中，我们有意地未涵盖潜在的潜力，并且没有进行NLS研究和MRI的对比分析来检测术后早期血肿，湿疹和出血等并发症。我们集中研究了他们根据切除的肿瘤床的术后变化检测是否存在并确定残留肿瘤大小的潜力。根据手术干预，对32例患者进行了全切开术--小计– 18例，部分–

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