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Predictors of first incidence of alcohol use disorders in the Lundby cohort from 1947-1997

机译:1947-1997年间伦德比队列中首次发生酒精使用障碍的预测因素

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Mattisson, C., Bogren, M., Horstmann, V., & ?jesj?, L. (2014). Predictors of first incidence of alcohol use disorders in the Lundby cohort from 1947-1997. The International Journal Of Alcohol And Drug Research, 3 (4), 257-267. doi: http://dx.doi.org/10.7895/ijadr.v3i4.185 Objective: Epidemiological evidence indicates an inverse relationship between socio-economic status (SES) and alcohol use disorder (AUD), although there are relatively few recent incidence studies. The present study aimed to assess the incidence of AUD by age, gender and SES and to analyse AUD’s association with mental disorder. Method: Information about mental disorders, including first incidence cases of AUD, was assessed in the Lundby cohort ( n =3,563) by field investigations in 1947, 1957, 1972 and 1997. Incidence calculations were based on 3,372 individuals without prior AUD. For the two genders, age-standardised incidences of AUD for the 25-year periods of 1947-1972 and 1972-1997 were compared. Possible risk factors for incident AUD were analysed by means of Cox regression analyses for the whole sample and for each sex separately. Results: A total of 233 first incidence AUD cases were detected (198 males, 35 females. Incidence rates, expressed as number of cases per 1000 person years, were highest for working class males at 5.46 cases per 1000 person years for the period 1 of July 1947, to 30 June 1972 and 4.77 for the period 1 of July 1972 to 30 June 1997, respectively. Middle class males showed intermediate incidence rates of 2.73 and 2.65. Self-employed males showed the lowest incidence rates of 2.50 and 1.47. Females generally had much lower incidence, although they showed a non-significant tendency for higher incidence rates in the latter period. A diagnosis of depressive disorders, anxiety disorders and unspecific neurotic states increased the risk for developing first incident AUD. Conclusion: Working class males had higher annual incidence of alcoholism in both time periods relative to middle class and self-employed males. Mental disorder increased the risk for AUD among both genders.
机译:Mattisson,C.,Bogren,M.,Horstmann,V.,&?jesj ?, L.(2014)。 1947-1997年在伦德比队列中首次发生酒精使用障碍的预测因素。国际酒精与药物研究杂志,3(4),257-267。 doi:http://dx.doi.org/10.7895/ijadr.v3i4.185目的:流行病学证据表明,社会经济状况(SES)与饮酒障碍(AUD)之间呈反比关系,尽管近期发病率相对较低学习。本研究旨在按年龄,性别和SES评估AUD的发生率,并分析AUD与精神障碍的关联。方法:通过1947年,1957年,1972年和1997年的田野调查,在伦德比队列(n = 3,563)中评估了有关精神疾病的信息,包括首次发生的AUD病例。发病率的计算基于没有AUD的3,372个人。对于这两种性别,比较了1947-1972年和1972-1997年这25年间按年龄标准化的澳元发病率。通过Cox回归分析对整个样本和每个性别分别进行分析,以分析可能发生AUD的危险因素。结果:总共发现233例AUD初次发病(男性198例,女性35例。在发病率1中,以每千人年的病例数表示),工人阶级男性的发病率最高,为每千人5.46例。 1947年7月至1972年6月30日和1972年7月1日至1997年6月30日的4.77分别为中产阶级男性,发生率分别为2.73和2.65,自营职业男性的发生率最低,为2.50和1.47。尽管他们在后期没有较高的发病率趋势,但总体上发病率要低得多;诊断为抑郁症,焦虑症和非特异性神经症的人会增加首次发病澳元的风险。相对于中产阶级和自营职业的男性,这两个时期的酒精中毒年发病率均较高;心理障碍增加了两性中患澳元的风险。

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