...
首页> 外文期刊>The Internet Journal of Orthopedic Surgery >Total Antioxidant Capacity Of HDL In Patients Before And After Coronary Surgery
【24h】

Total Antioxidant Capacity Of HDL In Patients Before And After Coronary Surgery

机译:冠状动脉手术前后患者HDL的总抗氧化能力

获取原文
           

摘要

During the postoperative period following cardiopulmonary bypass (CPB), oxygen free radicals are generated by the whole body inflammatory response. Intracellular and extracellular compartments possess defense mechanisms against oxygen free radical damage referred namely "antioxidant status". The purpose of this study was to investigate the early postoperative changes of total antioxidant capacity of HDL in patients before and after coronary surgery. Eleven patients undergoing coronary artery bypass surgery participated in this study and their HDL was obtained from both preoperative and 2-day postoperative plasma by sequential ultracentrifugation. Total antioxidant capacity of HDL was measured by using radical cation decolorization (TEAC) assay. Using student"s t-test, total antioxidant status of HDL from most patients remained unchanged for at 2 days after operation (p>0.05). Further studies are required in more patients and at prolonged interval times.
机译:在体外循环(CPB)后的术后期间,全身炎症反应会产生氧自由基。细胞内和细胞外区室具有抵抗氧自由基损伤的防御机制,称为“抗氧化剂状态”。这项研究的目的是调查冠状动脉手术前后患者HDL总抗氧化能力的早期术后变化。 11名接受冠状动脉搭桥手术的患者参加了这项研究,他们的HDL是通过连续超速离心从术前和术后2天血浆中获得的。 HDL的总抗氧化能力通过使用自由基阳离子脱色(TEAC)分析进行测量。使用学生t检验,大多数患者HDL的总抗氧化剂状态在手术后2天保持不变(p> 0.05)。需要对更多的患者进行更深入的研究,并要延长间隔时间。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号