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Preop Fluid Bolus Reduces Risk Of Post Op Nausea And Vomiting: A Pilot Study

机译:一项初步研究表明,术前液体小丸可降低术后恶心和呕吐的风险

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Postoperative nausea and vomiting (PONV) are distressing and common occurrences after operative procedures requiring general anesthesia. The purpose of this study was to determine the effect of a preoperative one liter fluid bolus of normal saline on a patient's post operative nausea and vomiting. This pilot study compared the incidence of nausea and vomiting between an experimental group who received a 1-liter fluid bolus pre-operatively, and a control group who were given the standard fluid requirements. Subjects consisted of 90 females who underwent gynecological laproscopic surgery.The two groups were evenly divided, with 45 in each group. There was no difference in the mean age of the two groups. The average age in the control and the study groups was 33. The weight of the control group was significantly higher, 80 kg vs. 69 kg in the experimental group (p=.018). Thirty percent of the control group had nausea and five percent experienced vomiting. The experimental group had a twelve percent nausea rate and no vomiting. When episodes of nausea and vomiting were combined, there was a significant difference between the groups (p=.001). Fifty-one percent of the control group had an episode of nausea/vomiting while only seventeen percent of the experimental group experienced nausea or vomiting. Our findings suggest that administering a liter of saline fluid bolus decreases the incidence of nausea and vomiting in this population. Further studies need to examine the use of hydration without the use of antiemetics and control for other factors that might affect nausea and vomiting.
机译:术后恶心和呕吐(PONV)令人痛苦,并且在需要全身麻醉的手术程序后屡见不鲜。这项研究的目的是确定术前一升生理盐水补液对患者术后恶心和呕吐的影响。这项前瞻性研究比较了术前接受1升液体推注的实验组与接受标准补液要求的对照组之间的恶心和呕吐发生率。受试者由90位接受妇科腹腔镜手术的女性组成,两组均分,每组45人。两组的平均年龄没有差异。对照组和研究组的平均年龄为33岁。对照组的体重明显更高,分别为80千克和实验组的69千克(p = .018)。对照组中有30%的人有恶心,而有5%的人有呕吐。实验组的恶心率为12%,无呕吐。当恶心和呕吐发作合并在一起时,两组之间存在显着差异(p = .001)。对照组中有51%出现恶心/呕吐,而实验组中只有17%出现恶心或呕吐。我们的研究结果表明,在该人群中使用一升生理盐水推注可减少恶心和呕吐的发生率。进一步的研究需要检查在不使用止吐药的情况下使用水合的情况,并控制可能影响恶心和呕吐的其他因素。

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