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首页> 外文期刊>The Internet Journal of Academic Physician Assistants >Dramatic And Long Lasting Efficiency (13 Years) Of Oral 5 Aspirin
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Dramatic And Long Lasting Efficiency (13 Years) Of Oral 5 Aspirin

机译：口服5阿司匹林具有惊人而持久的功效（13年）

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Introduction: Could 5 ASA be an option in case of cortico-resistant and/or intolerant ulcerative colitis?Case report: A 55-year-old woman was referred for a recent, moderately severe, left-sided ulcerative colitis. The response to corticotherapy was initially fair, then mediocre, complicated by a severe depression. The patient rejected colectomy. Corticotherapy was switched to 3g/d oral PentasaR. Bleeding stopped and rectal mucosa switched to pink within 3 days. Colonoscopy, performed 10 days later, evidenced deep and large ulcerations in the process of cicatrization.After 13 years of 5-ASA, the patient remains asymptomatic with progressive disappearance of mucosal scars.Conclusion: Oral 5 ASA could be worth a trial in some cases of severe flare-ups of ulcerative colitis when corticoids are inefficient or poorly tolerated and if colectomy is not possible, as an alternative to cyclosporin. The quick and long-lasting efficiency in the present case are to be emphasized.
机译：简介：如果对皮质类药物耐药和/或不耐受的溃疡性结肠炎，可以选择5种ASA吗？病例报告：一名55岁的妇女因近期中度严重的左侧溃疡性结肠炎而被转诊。最初对皮质疗法的反应是中等的，然后是中等的，并伴有严重的抑郁症。病人拒绝结肠切除术。皮质疗法改为口服3g / d PentasaR。在3天内出血停止，直肠粘膜变成粉红色。 10天后进行的结肠镜检查显示瘢痕形成过程中存在深层和大溃疡.5-ASA 13年后，患者仍无症状，粘膜瘢痕逐渐消失。结论：在某些情况下，口服5 ASA值得一试当皮质激素治疗无效或耐受不良且无法行结肠切除术时，溃疡性结肠炎的严重发作可替代环孢菌素。在当前情况下，要强调快速和持久的效率。

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