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Monitoring Disease Activity in Asthma

机译:监测哮喘中的疾病活动

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摘要

Asthma is characterized by waxing and waning episodic wheezing, reversible airway obstruction, bronchial hyperresponsiveness, and chronic inflammation of the airways. It is often considered a gene-environment interaction. This means that, even with a genetic predisposition toward asthma, development of disease may not occur without proper environmental priming or exposure (1,2). In all likelihood, asthma consists of many genetic diseases that interact with many environments, with only some of the gene-environment interactions resulting in the constellation of findings consistent with the asthma syndrome. Without thinking, we label this syndrome a disease because it has many characteristics consistent with a disease.
机译:哮喘的特征是发作性喘息逐渐消退,可逆性气道阻塞,支气管高反应性和气道慢性炎症。它通常被认为是基因与环境的相互作用。这意味着,即使对哮喘有遗传易感性,没有适当的环境引发或暴露也不会发生疾病的发展(1,2)。哮喘很可能由许多与多种环境相互作用的遗传性疾病组成,只有某些基因-环境相互作用导致与哮喘综合征一致的发现。不用考虑,我们将此综合征称为疾病,因为它具有与疾病相符的许多特征。

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