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The Hygiene Hypothesis and the Primary Prevention of Allergic Diseases

机译:卫生假说与过敏性疾病的初步预防

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It has been suggested that there has been an increase in atopy and allergic diseases over the last 30 years; these diseases include allergic rhinitis, atopic asthma, and atopic dermatitis. Multiple explanations have been proffered to explain the increase in atopy and related diseases with the hygiene hypothesis the front-running theory. Before addressing the mechanism of the increase in such atopic diseases, it must be questioned whether allergic diseases have really increased. When isolating atopic asthma as the disease of interest, it is unclear whether or not there has actually been an increase in incidence of this disease.
机译:有人建议,在过去的30年中,特应性疾病和过敏性疾病有所增加。这些疾病包括过敏性鼻炎,特应性哮喘和特应性皮炎。已经提出了多种解释,以卫生假说作为先行理论来解释特应性疾病和相关疾病的增加。在探讨此类特应性疾病增加的机制之前,必须质疑过敏性疾病是否确实有所增加。当将特应性哮喘分离为目标疾病时,尚不清楚该疾病的发病率实际上是否有所增加。

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