The key role of vitamin A in spermatogenesis

Cathryn A. Hogarth; Michael D. Griswold

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The key role of vitamin A in spermatogenesis

机译：维生素A在精子发生中的关键作用

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Spermatogenesis in adult mammals is highly organized, with the goal being continual sperm production. Vertebrate testes are arranged into recurring cellular associations that vary with time and distance along the tubule. These changes over time and distance are designated the cycle of the seminiferous epithelium and the spermatogenic wave, respectively. In this Review, we briefly outline the roles that follicle-stimulating hormone (FSH) and testosterone play in regulating spermatogenesis and describe our current understanding of how vitamin A regulates germ cell differentiation and how it may lead to the generation of both the cycle of the seminiferous epithelium and the spermatogenic wave.

机译：成年哺乳动物的精子发生高度组织化，目标是持续产生精子。脊椎动物的睾丸被排列成反复出现的细胞联想，这些联想随着时间和沿肾小管的距离而变化。这些随时间和距离的变化分别被称为生精上皮和生精波的周期。在本综述中，我们简要概述了卵泡刺激素（FSH）和睾丸激素在调节精子发生中的作用，并描述了我们目前对维生素A如何调节生殖细胞分化以及如何导致维生素A循环的理解。生精上皮和生精波。

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《The journal of clinical investigation》 |2010年第4期|共7页
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Cathryn A. Hogarth; Michael D. Griswold;
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The key role of vitamin A in spermatogenesis

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