...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The Journal of Musculoskeletal and Neuronal Interactions >Atypical femoral fracture in a beta-thalassemia major patient with previous bisphosphonate use: case report and a review of the literature
【24h】

Atypical femoral fracture in a beta-thalassemia major patient with previous bisphosphonate use: case report and a review of the literature

机译：曾使用双膦酸盐的β-地中海贫血重症患者的非典型股骨骨折：病例报告和文献复习

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

There are numerous studies presenting the beneficial effect of bisphosphonates (BPs) on bone disease of patients suffering from beta-thalassemia major (TM). Although BPs have been widely used, adverse events have been described including atypical femoral fractures (AFF). In the present case, a male adult patient suffering from TM sustained an AFF fulfilling all major and two minor crite- ria. Before AFF, the patient had been treated with zoledronic acid for three years and remained another one year without osteoporosis therapy. To our knowledge, this is the first reported case of AFF in a patient suffering from TM, probably due to the small sample size of patients with thalassemia. The purpose of the present case is to increase the awareness amongst haematologists, who mainly deal with TM patients, of the adverse events of BP use.
机译：有大量研究表明双膦酸盐（BPs）对患有严重β-地中海贫血（TM）的患者的骨病具有有益的作用。尽管BP已被广泛使用，但已描述了不良事件，包括非典型股骨骨折（AFF）。在本例中，一名患有TM的成年男性患者持续满足所有主要和两个次要标准的AFF。在进行AFF之前，该患者已经接受唑来膦酸治疗了三年，并且再过一年没有接受骨质疏松症治疗。据我们所知，这是首次报道的患有TM的AFF患者，这可能是由于地中海贫血患者的样本量较小。本案例的目的是提高主要针对TM患者的血液科医生对BP使用不良事件的认识。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号