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首页> 外文期刊>The Journal of Musculoskeletal and Neuronal Interactions >Effects of eccentric exercise on different slopes
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Effects of eccentric exercise on different slopes

机译：偏心运动对不同坡度的影响

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Objectives: Eccentric contraction occurs when the muscle lengthens under tension. Damage-induced responses seenin the muscle after eccentric exercise usually experienced by sedentary individuals. This study aims to investigate muscledamage on different slopes. Methods: 32 male Wistar albino rats randomly divided into four groups: sedentary, horizontalrunning, and eccentric exercise (-8°, -16°) groups. Animals ran for 90 min with the speed of 25 m/s for five days. After48h from the last exercise, rats were sacrificed, and plasma creatine kinase (CK), heat shock protein 70 (HSP70) levelswere examined. Plasma and soleus total oxidant/antioxidant status (TOS-TAS) and histological changes of soleus muscleassessed. Results: CK and HSP70 significantly increased in 16° EE group. TOS increased at 16° EE and 8° EE, but oxidativestress index (OSI) was only high at 8? EE group. Mononuclear cell infiltration and the angiogenesis increased in soleus aftereccentric exercise, and there was a correlation with slope. Sarcomere breaks were detected in 16° EE group also in acorrelation with slope. Conclusions: Consequently, sedentary individuals are vulnerable to injuries induced by eccentriccontraction. Therefore, our study provides information for reconsidering rehabilitation and training programs.
机译：目标：当肌肉在张力下伸长时，会发生离心收缩。久坐不动的人通常会在离心运动后在肌肉中看到损伤引起的反应。这项研究旨在调查不同斜坡上的肌肉损伤。方法：32只雄性Wistar白化病大鼠随机分为四组：久坐，水平跑步和离心运动（-8°，-16°）组。动物以25 m / s的速度跑了90分钟，持续了五天。在最后一次运动后48h，处死大鼠，并检查血浆肌酸激酶（CK），热休克蛋白70（HSP70）水平。评估血浆和比目鱼的总氧化剂/抗氧化剂状态（TOS-TAS）以及比目鱼肌的组织学变化。结果：EE组和16°EE组的CK和HSP70显着升高。在16°EE和8°EE时，TOS升高，但是氧化应激指数（OSI）仅在8？时较高。 EE组。比目鱼偏心运动后单核细胞浸润和血管生成增加，并且与斜率相关。在16°EE组也发现肌节断裂，也与斜率相关。结论：因此，久坐不动的人容易受到离心收缩引起的伤害。因此，我们的研究为重新考虑康复和培训计划提供了信息。

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