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Breast Tuberculosis: Still Common In India

机译:乳房结核:在印度仍然很普遍

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Breast tuberculosis is a rare form of tuberculosis. In last three years 1016 patients of breast lump were referred to single unit of pathology department. FNAC was performed in all the cases and 770 patients (75%) were diagnosed as benign breast disease while 246 patients (25%) were malignant. Out of 770 cases of benign disease, 42 patients (4.13%) had tuberculosis of breast. The mean age of the patient with tuberculosis was 33.71 year. 41 patients were female and one was male. 8 patients (19.04%) were lactating at the time of presentation. Most of these lumps were clinically misdiagnosed as benign breast disease (29cases) or malignancy (8 cases). In conclusion, although breast tuberculosis is extremely rare in developed countries but it is still common in developing countries like India. The diagnosis can be easily made from the FNAC of the suspected lump. Introduction Tuberculosis is a worldwide problem with high incidence in endemic area such as India and East Asia (1). Progress in antituberculous chemotherapy, socioeconomic improvement, and proper isolation of patients has lead to a decline in the incidence of tuberculosis during the past few decades. Recently, tuberculosis has increased in many industrialized countries due to increased number of immunocompromised and AIDS patients. As the incidence of tuberculosis increases, an increase in extrapulmonary involvement can be expected (2,3,4). In earlier reports from the developing countries show the incidence of breast tuberculosis is 3-4.5 %, but it is rare in developed countries (0.6-1.6 %)(5,6). The present study gives the spectrum of benign breast lump with extent of tubercular mastitis prevalent in India. Material and Method During the period of three years between September 2001 to August 2004, 1016 breast lumps were referred to single unit of pathology department for FNAC. FNAC was performed in all patients using 22gauge disposable needle attached to 10ml plastic syringe. Two to three different areas in breast lump were aspirated in each case. Three to four slides were prepared per case, two were fixed in methanol for Papinicolaou staining and the remaining slides were air dried for May-Grunwald-Giemsa stain. After the slides were screened, Ziehl – Neelsen staining for AFB was done in every patient of tubercular lesion. Results Out of 1016 breast lump cases, 770 (75%) were benign and 246 (25%) were malignant. The spectrum of benign breast disease is shown in Table 1. Fibroadenosis was the commonest benign lump (42.46%), followed by fibroadenoma (30.25%). The mean age of the patient with fibroadenosis was 30.43 year and fibroadenoma was 23.92 year.
机译:乳腺癌是一种罕见的结核病。在最近三年中,有1016例乳房肿块患者被转诊到病理科。所有病例均行FNAC检查,其中770例(75%)被诊断为良性乳腺疾病,而246例(25%)为恶性。在770例良性疾病中,有42例(4.13%)患有乳腺结核。结核病患者的平均年龄为33.71岁。女性41例,男性1例。在报告时有8名患者(19.04%)正在哺乳。这些肿块大多数在临床上被误诊为良性乳腺疾病(29例)或恶性肿瘤(8例)。总之,尽管乳腺结核在发达国家极为罕见,但在像印度这样的发展中国家仍然很普遍。可以从疑似肿块的FNAC轻松诊断。引言结核病是一个世界性的问题,在印度和东亚等流行地区发病率很高(1)。在过去的几十年中,抗结核化疗的进展,社会经济的改善以及对患者的正确隔离导致了结核病发病率的下降。最近,由于免疫功能低下和艾滋病患者的数量增加,在许多工业化国家中结核病有所增加。随着结核病发病率的增加,预计肺外受累也会增加(2、3、4)。在发展中国家的较早报告中显示,乳腺结核的发病率为3-4.5%,但在发达国家很少见(0.6-1.6%)(5,6)。本研究给出了在印度流行的乳腺肿块的频谱与结核性乳腺炎的程度。材料和方法在2001年9月至2004年8月的三年中,将1016个乳房肿块转诊给FNAC的病理学部门。所有患者均使用连接在10ml塑料注射器上的22号一次性针头进行FNAC。在每种情况下,均吸出两到三个乳房肿块。每箱准备三到四个载玻片,其中两个固定在甲醇中进行Papinicolaou染色,其余的载玻片风干以进行May-Grunwald-Giemsa染色。筛选载玻片后,对每位结核病患者进行Ziehl-Neelsen AFB染色。结果在1016例乳腺肿块中,良性770例(75%),恶性246例(25%)。乳腺良性疾病的频谱示于表1。纤维腺瘤病是最常见的良性肿块(42.46%),其次是纤维腺瘤(30.25%)。纤维腺瘤病患者的平均年龄为30.43岁,纤维腺瘤瘤的平均年龄为23.92岁。

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