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首页> 外文期刊>The Korean Journal of Parasitology >A follow-up study to evaluate the efficacy of mass chemotherapy for control of paragonimiasis
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A follow-up study to evaluate the efficacy of mass chemotherapy for control of paragonimiasis

机译：评估大规模化疗控制肺吸虫病疗效的后续研究

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In the survey of l1,005 subjects in l3 villages of Che Ju lsland, 1,450 persons were egg-positive by repeated sputum examinations. The response rate to intradermal test ranged 50-80% of the population and to sputum examination for skin positive 60-70% in the first survey done in l964. 93% of all egg-positive was treated with 40 mg/kg body weight of bithionol on alternate days for 10-15 doses in l965. Follow-up studies were carried out in one year, three-year, five-year, and eight year after the mass treatment. The one year follow-up study covered 86.5% of all treated cases in all villages but only a part of the population of a few villages in further follow-up studies. In this paper only the result obtained from the age group of 7-18 years, the common population studied in every follow-up for the purpose of comparison, is presented. Intermediate hosts of P. westermani were examined at the same time. In one year follow-up it was found that 91% of egg-positive treated became negative.
机译：在Che Ju岛的3个村庄对1,005名受试者进行的调查中，通过反复进行痰液检查，有1,450人呈鸡蛋阳性。在1964年进行的首次调查中，对皮内测试的反应率为50-80％，对皮肤阳性的痰检查的响应率为60-70％。在1965年，隔天用40 mg / kg体重的苯硫酚处理所有鸡蛋阳性的93％，剂量为10-15剂。大规模治疗后的一年，三年，五年和八年进行随访研究。一年的随访研究覆盖了所有村庄所有病例的86.5％，但在进一步的随访研究中仅覆盖了少数村庄的一部分人口。本文仅介绍了从7-18岁年龄组获得的结果，该年龄组在每次随访中均进行了研究，以进行比较。同时研究了P. westermani的中间宿主。在一年的随访中，发现91％的鸡蛋阳性患者转为阴性。

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