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首页> 外文期刊>The Korean Journal of Parasitology >A Case of Pentastomiasis at the Left Maxilla Bone in a Patient with Thyroid Cancer
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A Case of Pentastomiasis at the Left Maxilla Bone in a Patient with Thyroid Cancer

机译:甲状腺癌患者左上颌骨黄斑粉刺一例

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摘要

Pentastomiasis, a zoonotic parasite infection, is typically found in the respiratory tract and viscera of the host, including humans. Here, we report for the first time an extremely rare case of intraosseous pentastomiasis in the human maxilla suffering from medication related osteonecrosis of the jaw (MRONJ). A 55-year-old male had continuously visited the hospital for MRONJ which had primarily developed after bisphosphonate and anti-neoplastic administration for previous bone metastasis of medullary thyroid cancer. Pain, bone exposure, and pus discharge in the right mandible and left maxilla were seen. Osteolysis with maxillary cortical bone perforation at the left buccal vestibule, palate, nasal cavity, and maxillary sinus was observed by radiologic images. A biopsy was done at the left maxilla and through pathological evaluation, a parasite with features of pentastome was revealed within the necrotic bone tissue. Further history taking and laboratory evaluation was done. The parasite was suspected to be infected through maxillary open wounds caused by MRONJ. Awareness of intraosseous pentastomiasis should be emphasized not to be missed behind the MRONJ. Proper evaluation and interpretation for past medical history may lead to correct differential diagnosis and therapeutic intervention for parasite infections.
机译:猪瘟是一种人畜共患的寄生虫感染,通常在包括人类在内的宿主的呼吸道和内脏中发现。在这里,我们首次报道了极少见的人类上颌骨中发生骨内戊状扩张的病例,其发生了与药物相关的颌骨坏死(MRONJ)。一名55岁的男性不断前往MRONJ医院就诊,MRONJ最初是在双膦酸盐和抗肿瘤药物治疗后因甲状腺髓样癌的骨转移而发展的。观察到右下颌骨和左上颌骨有疼痛,骨骼暴露和脓液排出。影像学检查发现左颊前庭,上late,鼻腔和上颌窦有上颌骨皮质穿孔。在左上颌骨进行活检,并通过病理学评估,在坏死骨组织内发现了具有五角星形特征的寄生虫。进行了进一步的历史记录和实验室评估。怀疑该寄生虫是由MRONJ造成的上颌开放伤口感染的。 MRONJ背后不应该遗忘骨内弥散性肺炎的意识。对过去的病史进行正确的评估和解释可能会导致针对寄生虫感染的正确鉴别诊断和治疗干预。

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