...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The Korean Journal of Physiology & Pharmacology >c-Fos Expression in the Nucleus of the Solitary Tract in Response to Salt Stimulation in Rats
【24h】

c-Fos Expression in the Nucleus of the Solitary Tract in Response to Salt Stimulation in Rats

机译：盐刺激对大鼠孤束核中c-Fos表达的影响

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Salt signals in tongue are relayed to the nucleus of the solitary tract (NST). This signaling is very important to determine whether to swallow salt-related nutrition or not and suggests some implications in discrimination of salt concentration. Salt concentration-dependent electrical responses in the chorda tympani and the NST were well reported. But salt concentration-dependency and spatial distribution of c-Fos in the NST were not well established. In the present study, NaCl signaling in the NST was studied in urethane-anesthetized rats. The c-Fos immunoreactivity in the six different NST areas along the rostral-caudal axis and six subregions in each of bilateral NST were compared between applications of distilled water and different concentrations of NaCl to the tongue of experimental animals. From this study, salt stimulation with high concentration (1.0 M NaCl) induced significantly higher c-Fos expression in intermediate NST and dorsal-medial and dorsal-middle subregions of the NST compared to distilled water stimulation. The result represents the specific spatial distribution of salt taste perception in the NST.
机译：舌头中的盐信号传递到孤立道（NST）的核。该信号对于确定是否吞咽盐相关营养非常重要，并暗示了对盐浓度判别的一些含义。在鼓膜和NST中盐浓度依赖的电响应已有很好的报道。但是在NST中盐浓度依赖性和c-Fos的空间分布尚不明确。在本研究中，在氨基甲酸乙酯麻醉的大鼠中研究了NST中的NaCl信号传导。比较了在实验动物的舌头上使用蒸馏水和不同浓度的NaCl时，沿鼻尾轴的六个不同NST区域和每个双边NST的六个子区域中的c-Fos免疫反应性。根据这项研究，与蒸馏水刺激相比，高浓度（1.0 M NaCl）的盐刺激在NST的中间NST以及背内侧和背中间中间区域诱导了更高的c-Fos表达。结果代表了NST中盐味感知的特定空间分布。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号