首页> 外文期刊>The Open Anesthesia Journal >A Randomized, Double Blind Study to Evaluate the Efficacy of Palonosetron with Dexamethasone Versus Palonosetron Alone for Prevention of Post-Operative Nausea and Vomiting in Subjects Undergoing Bariatric Surgeries with High Emetogenic Risk
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A Randomized, Double Blind Study to Evaluate the Efficacy of Palonosetron with Dexamethasone Versus Palonosetron Alone for Prevention of Post-Operative Nausea and Vomiting in Subjects Undergoing Bariatric Surgeries with High Emetogenic Risk

机译:评估帕洛诺司琼与地塞米松与单独使用帕洛诺司琼对预防高脂血症性肥胖手术的患者手术后恶心和呕吐的效果的随机,双盲研究

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Introduction:Postoperative (PONV) and postdischarge (PDNV) nausea and vomiting are common (60-70%) after bariatric surgery. Palonosetron (Pal), a novel 5-HT3 antagonist, is an effective antiemetic with a prolonged duration of action in the setting of PDNV. We hypothesized that combination therapy with Palonosetron (Pal) and dexamethasone (Dex) would improve treatment in comparison to Palonosetron alone in patients at high risk for PONV.
机译:简介:减肥手术后,常见的是术后(PONV)和出院后(PDNV)恶心和呕吐(60-70%)。帕洛诺司琼(Pal)是一种新型的5-HT3拮抗剂,是一种有效的止吐药,在PDNV的治疗中作用时间延长。我们假设,与仅使用帕洛诺司琼的PONV高危患者相比,帕洛诺司琼(Pal)和地塞米松(Dex)联合治疗将改善治疗。

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