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首页> 外文期刊>The Open Complementary Medicine Journal >Cytoprotective Activity of Cissus quadrangularis Linn Variant I AgainstGastric and Duodenal Ulcer in Rat Models
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Cytoprotective Activity of Cissus quadrangularis Linn Variant I AgainstGastric and Duodenal Ulcer in Rat Models

机译：四倍体Cissus quadrangularis Linn变体I对大鼠模型的胃和十二指肠溃疡的细胞保护活性

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摘要

The square stemmed variety of Cissus quadrangularis L. variant I is a medicinal plant widely used for pepticulcer and bone fractures in Indian Systems of Medicine. Though this medicinal plan is abundantly used in India, detailedstudies are lacking on the variants and seasonal variations, which are to be addressed. The present study is carried out toevaluate the antiulcerogenic property of aqueous ethanolic extracts of the aerial parts in various ulcer models in animals.The study clearly elucidated that the drug was found to increase the defensive factors by virtue of its ulcer score, carbohydrateprotein ratio and decrease in aggressive factors like free acidity, pepsin apart from other biochemical parameters.Plants collected during flowering season are more effective than that collected during vegetative seasons. Extract significantlyreduced the formation of gastric and duodenal lesions by virtue of its cyto-protective and mucin productive activities.
机译：方型变种Cissus quadrangularis L.variant I是印度植物医学中广泛用于消化性溃疡和骨折的药用植物。尽管该药物计划在印度得到了广泛的应用，但仍缺乏有关变体和季节性变化的详细研究，需要加以解决。本研究旨在评估动物各种溃疡模型中地上部分含水乙醇提取物的抗溃疡原性。研究清楚地表明，该药物由于其溃疡评分，糖蛋白比率和降低而增加了防御因子。除了游离生酸，胃蛋白酶等侵略性因素外，开花季节收集的植物比植物生长季节收集的植物更有效。提取物凭借其细胞保护和粘蛋白生产活性，显着减少了胃和十二指肠病变的形成。

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