Management and Treatment Guidelines for Sepsis in Pediatric Patients

NidalEl-wiher; TimothyT. Cornell; NiranjanKissoon; ThomasP. Shanley

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Management and Treatment Guidelines for Sepsis in Pediatric Patients

机译：小儿败血症的管理和治疗指南

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Sepsis remains one of the leading causes of morbidity and mortality in children despite improvedunderstanding of the pathophysiology leading to better clinical management and survival. Recent studies have identifiedseveral areas that must be addressed by the clinician in order to continue to impact the morbidity and mortality associatedwith sepsis. In this review, we discuss the evidence in several of these areas including initial resuscitation, pathogeneradication, maintenance of oxygen delivery, and directed modifiers of the inflammatory response. Our overall goal is toprovide the bedside clinician with an updated systematic approach to treat sepsis in children.

机译：尽管对病理生理学的理解有所改善，导致更好的临床管理和生存，败血症仍然是儿童发病和死亡的主要原因之一。最近的研究已经确定了临床医生必须解决的几个领域，以便继续影响败血症的发病率和死亡率。在这篇综述中，我们讨论了这些领域中的几个方面的证据，包括最初的复苏，病原体根除，维持氧气输送以及炎症反应的定向调节剂。我们的总体目标是为床边临床医生提供一种更新的系统性方法来治疗儿童败血症。

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《The Open Inflammation Journal》 |2011年第1期|共9页
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NidalEl-wiher; TimothyT. Cornell; NiranjanKissoon; ThomasP. Shanley;
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Management and Treatment Guidelines for Sepsis in Pediatric Patients

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