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首页> 外文期刊>The Open Infectious Diseases Journal >Successful Treatment of Psoriasis-like Lesions in HIV Infected Patients in Uganda with Chloroquine
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Successful Treatment of Psoriasis-like Lesions in HIV Infected Patients in Uganda with Chloroquine

机译：氯喹成功治疗乌干达HIV感染患者的牛皮癣样病变

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The effect of chloroquine in the treatment of psoriasis remains controversial. Treatment of psoriasis in HIVinfection is not well described. Chloroquine has been shown to have direct effects on both the Human ImmunodeficiencyVirus (HIV) and on the psoriasis disease process. The effect of chloroquine in HIV infected patients with psoriasis has notbeen well studied.We report on the effect of chloroquine on psoriasis-like lesions in three HIV infected patients who were not onantiretroviral therapy. Three consecutive HIV positive patients with CD4 cell count below 200cells/mm3 had unequivocalimprovement of their psoriasis-like lesions after 2 weeks of a daily dose of 150mg of chloroquine.In conclusion, chloroquine may be useful in the treatment of psoriasis-like lesions in patients with HIV infectionparticularly in resource poor settings. Ideally, a controlled clinical trial will be needed to confirm this.
机译：氯喹在银屑病治疗中的作用仍存在争议。 HIV感染中牛皮癣的治疗方法不完善。氯喹已被证明对人类免疫缺陷病毒（HIV）和牛皮癣疾病过程都有直接影响。氯喹对HIV感染的牛皮癣患者的作用尚未得到很好的研究。我们报道了氯喹对三名未接受抗逆转录病毒治疗的HIV感染患者的银屑病样病变的作用。连续三天的HIV阳性患者CD4细胞计数低于200cells / mm3，每天服用150mg氯喹2周后，其牛皮癣样病变得到了明确的改善。总而言之，氯喹可能对治疗患者的牛皮癣样病变有用感染艾滋病毒，尤其是在资源贫乏地区。理想情况下，将需要进行对照临床试验以确认这一点。

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