...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The Open Infectious Diseases Journal >Comparison of Macroscopic and Microscopic Assessment of Specimens Collected for the Diagnosis of Tuberculosis
【24h】

Comparison of Macroscopic and Microscopic Assessment of Specimens Collected for the Diagnosis of Tuberculosis

机译：宏观和微观标本评估对结核病诊断的评估的比较

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Diagnosis of tuberculosis in a field setting depends on the quality of specimens submitted for smearmicroscopy.Macroscopic assessment (sputum or saliva) of the specimen for suitability for further examination is commonpractice in routine care. We examined whether macroscopic assessment could correctly identify sputum specimens basedon four published algorithms using microscopic features in the setting of active case finding in a community survey.The study included 901 randomly selected adults who reported cough for 3 weeks or more in the national tuberculosisprevalence survey in Bangladesh. A single specimen of each was assessed with microscopy and microscopy (Gram-stain)to classify it as either sputum or saliva. The primary outcome was the agreement between the two assessment methods(Kappa statistic)From 901 specimens, 561 (62%) were macroscopically classified as saliva and 340 (38%) as sputum. From these, 888Gram-stained slides could be examined for microscopic features. The agreement between the macroscopic assessmentwith any of the four microscopy algorithms for sputum was very poor (all Kappa’s below 0.1).While macroscopic assessment of submitted specimens might be of value in routine care, it is not warranted in a setting ofactive case finding in a community survey. Submitting a specimen in the first place should be the primary goal in thissetting.
机译：在野外诊断结核病取决于要进行涂片显微镜检查的标本的质量。在常规护理中，对标本进行宏观检查（痰或唾液）是否适合进一步检查是常见的做法。在社区调查中，我们检查了宏观评估是否可以根据四种公开的算法使用微观特征正确识别痰标本，以进行社区病例调查中的活跃病例研究。该研究纳入了901名在2002年全国结核病患病率调查中报告咳嗽3周或更长时间的成年人。孟加拉国。通过显微镜和显微镜（Gram染色）评估每个样本的单个标本，将其分类为痰液或唾液。主要结果是两种评估方法之间的一致性（Kappa统计）从901个标本中，从宏观上将561个（62％）分类为唾液，将340个（38％）分类为痰。从中，可以检查888Gram染色的载玻片的微观特征。宏观评估与痰液的四种显微镜检查算法中的任何一种之间的一致性都非常差（所有Kappa值均低于0.1）。尽管对提交标本的宏观评估在常规护理中可能有价值，但在某些情况下不能发现主动病例社区调查。首先提交标本应该是此设置的主要目标。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号